Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:1856228 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
18553081856231924ornithine carbamoyltransferaseQuickGO ontologyBLASTP
18562281856740513arginine repressorQuickGO ontologyBLASTP
185674918579451197argininosuccinate synthaseQuickGO ontologyBLASTP
185802518594371413argininosuccinate lyaseQuickGO ontologyBLASTP
185954618606071062chalcone synthaseQuickGO ontologyBLASTP
186069018670706381polyketide synthase pks7QuickGO ontologyBLASTP
186709018718984809polyketide synthase pks8QuickGO ontologyBLASTP
187189818734061509polyketide synthase pks17QuickGO ontologyBLASTP
187341218764653054polyketide synthase pks9QuickGO ontologyBLASTP
187661218776731062chalcone synthaseQuickGO ontologyBLASTP
187765618789481293cytochrome P450 139 CYP139QuickGO ontologyBLASTP
187896318807381776macrolide ABC transporter ATP-binding proteinQuickGO ontologyBLASTP