Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:477500 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
477827478468642putative secreted proteinQuickGO ontologyBLASTP
4784754797041230putative lipoproteinQuickGO ontologyBLASTP
4797144809011188putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
480937481308372putative transmembrane proteinQuickGO ontologyBLASTP
4815034826061104putative transmembrane transport proteinQuickGO ontologyBLASTP
4826034843781776putative transmembrane transport proteinQuickGO ontologyBLASTP
484375484803429hypothetical proteinBLASTP
4851244868811758acyl-CoA synthetaseQuickGO ontologyBLASTP
4868784882601383putative membrane bound polyketide synthaseQuickGO ontologyBLASTP
4882474910872841putative membrane bound polyketide synthaseQuickGO ontologyBLASTP
491035491853819beta lactamase like proteinQuickGO ontologyBLASTP
4919314929411011putative F420-dependent glucose-6-phosphate dehydrogenaseQuickGO ontologyBLASTP
4929344950062073phosphate acetyltransferaseQuickGO ontologyBLASTP
4949994961561158acetate kinaseQuickGO ontologyBLASTP
4962104984622253serinethreonine-protein kinaseQuickGO ontologyBLASTP
498462499448987putative glutamine-binding lipoproteinQuickGO ontologyBLASTP
4994485007671320hypothetical proteinBLASTP