Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:1848091 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
184689218480941203acetylornithine aminotransferaseQuickGO ontologyBLASTP
18480911849014924ornithine carbamoyltransferaseQuickGO ontologyBLASTP
18490111849523513arginine repressorQuickGO ontologyBLASTP
184953218507281197argininosuccinate synthaseQuickGO ontologyBLASTP
185080818522201413argininosuccinate lyaseQuickGO ontologyBLASTP
185232918533901062putative chalcone synthaseQuickGO ontologyBLASTP
185347318598536381putative polyketide synthaseQuickGO ontologyBLASTP
185987318646784806putative polyketide synthaseQuickGO ontologyBLASTP
186467818661861509putative polyketide synthaseQuickGO ontologyBLASTP
186619218692453054putative polyketide synthaseQuickGO ontologyBLASTP