Pre_GI: BLASTP Hits

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Query: NC_015425:2072703:2097598 Clostridium botulinum BKT015925 chromosome, complete genome

Start: 2097598, End: 2098053, Length: 456

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_010334:722408:730938730938731399462Shewanella halifaxensis HAW-EB4, complete genomehypothetical protein4e-26116
NC_019978:2532640:254125625412562541705450Halobacteroides halobius DSM 5150, complete genomeuncharacterized protein, YhcH/YjgK/YiaL family5e-26116
NC_020291:4305521:430998543099854310440456Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomehypothetical protein2e-23108
NC_016048:3667890:367458336745833675035453Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein2e-1788.2
NC_013204:2305140:230843123084312308886456Eggerthella lenta DSM 2243, complete genomehypothetical protein5e-1786.7
NC_009708:1497898:151553315155331516003471Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein1e-1685.5
NC_006155:3237990:323799032379903238460471Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein1e-1685.5
NC_010634:3155741:315574131557413156211471Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein3e-1684
NC_013956:595320:631839631839632444606Pantoea ananatis LMG 20103 chromosome, complete genomeYiaL1e-1375.5
NC_015968:511282:515222515222515674453Enterobacter asburiae LF7a chromosome, complete genomehypothetical protein7e-1372.8
NC_006155:3040769:304423930442393044706468Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein4e-1270.5
NC_003143:2849377:285284628528462853313468Yersinia pestis CO92, complete genomehypothetical protein4e-1270.5
NC_005810:2613456:261692526169252617392468Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein4e-1270.5
NC_010159:1861465:186493418649341865401468Yersinia pestis Angola, complete genomehypothetical protein4e-1270.5
NC_008149:2411161:241463024146302415097468Yersinia pestis Nepal516, complete genomehypothetical protein4e-1270.5
NC_010634:2960000:296214729621472962614468Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein4e-1270.5
NC_010465:1724000:174170017417001742167468Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein4e-1270.5
NC_009708:1694685:171030017103001710767468Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein4e-1270.5
NC_017154:3139614:315665831566583157125468Yersinia pestis D106004 chromosome, complete genomehypothetical protein4e-1270.5
NC_017160:2740870:275626727562672756734468Yersinia pestis D182038 chromosome, complete genomehypothetical protein4e-1270.5
NC_017168:2892000:290912329091232909590468Yersinia pestis A1122 chromosome, complete genomehypothetical protein4e-1270.5
NC_017265:1521276:153993915399391540406468Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein4e-1270.5
NC_015061:3840463:386303738630373863690654Rahnella sp. Y9602 chromosome, complete genomeConserved hypothetical protein CHP000225e-1166.6
NC_017047:3907854:393045139304513931104654Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein5e-1166.6
NC_008800:1497746:151648215164821516949468Yersinia enterocolitica subsp. enterocolitica 8081 chromosome,hypothetical protein2e-1064.7
NC_016641:373623:388463388463388921459Paenibacillus terrae HPL-003 chromosome, complete genomeputative beta-D-galactosidase3e-1063.9
NC_011742:4795733:480429648042964804748453Escherichia coli S88 chromosome, complete genomehypothetical protein4e-1063.9
NC_010658:4494103:450437245043724504824453Shigella boydii CDC 3083-94, complete genomehypothetical protein6e-1063.2
NC_007613:4217557:424708642470864247547462Shigella boydii Sb227, complete genomehypothetical protein6e-1063.2
NC_012947:3947238:395551739555173955969453Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein6e-1063.2
NC_012967:4449576:445813944581394458591453Escherichia coli B str. REL606 chromosome, complete genomehypothetical protein6e-1063.2
NC_010498:4821519:483008348300834830535453Escherichia coli SMS-3-5, complete genomehypothetical protein8e-1062.8
NC_008570:4009762:402845640284564028926471Aeromonas hydrophila subsp. hydrophila ATCC 7966, complete genomehypothetical protein1e-0962
AC_000091:4472000:447954244795424479994453Escherichia coli W3110 DNA, complete genomehypothetical protein2e-0961.6
NC_010473:4564590:457469345746934575145453Escherichia coli str. K-12 substr. DH10B, complete genomehypothetical protein2e-0961.6
NC_000913:4462782:447288544728854473337453Escherichia coli K12, complete genomehypothetical protein2e-0961.6
NC_015061:4203767:424176942417694242239471Rahnella sp. Y9602 chromosome, complete genomeConserved hypothetical protein CHP000222e-0961.6
NC_017047:4298207:433565443356544336124471Rahnella aquatilis HX2 chromosome, complete genomehypothetical protein2e-0961.6
NC_010803:2067539:209042920904292090881453Chlorobium limicola DSM 245, complete genomehypothetical protein3e-0960.8
NC_013508:1491945:149442714944271494894468Edwardsiella tarda EIB202, complete genomehypothetical protein4e-0960.1
NC_014500:4049384:407327940732794073908630Dickeya dadantii 3937 chromosome, complete genomeProtein yjgK6e-0753.1
NC_009348:3819271:384048638404863840956471Aeromonas salmonicida subsp. salmonicida A449, complete genomehypothetical protein6e-0753.1
NC_020418:1397112:141131314113131411786474Morganella morganii subsp. morganii KT, complete genomePutative sugar isomerase involved in processing of exogenous sialic acid2e-0651.2
NC_014965:2200974:222025322202532220720468Vibrio vulnificus MO6-24/O chromosome I, complete sequencesugar isomerase3e-0650.4