Pre_GI Gene

Some Help

Host: NC_007613 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007613:4217557 Shigella boydii Sb227, complete genome

Host Lineage: Shigella boydii; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic that took place in China in the 1950s. Causes dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. Shigella boydii is uncommon except in India, where it was first isolated. Progression to clinical dysentery occurs in most patients infected with this organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
421755742198902334putative DNA primaseQuickGO ontologyBLASTP
42199054220225321putative protein encoded in prophageQuickGO ontologyBLASTP
42203614220816456hypothetical proteinBLASTP
42210894221688600putative bacteriophage proteinQuickGO ontologyBLASTP
42216854221951267hypothetical proteinBLASTP
42225034223237735hypothetical proteinBLASTP
42238084224380573phage polarity suppression proteinQuickGO ontologyBLASTP
422477842258571080hypothetical proteinBLASTP
42264024227355954hypothetical proteinBLASTP
422741042286751266putative P4-type integraseQuickGO ontologyBLASTP
4228827422891185tRNA-LeuQuickGO ontologyBLASTP
422906542301261062putative oxidoreductaseQuickGO ontologyBLASTP
423025642317581503hypothetical proteinBLASTP
423191942330041086hypothetical proteinBLASTP
423300142341011101hypothetical proteinBLASTP
423436842358791512aminopeptidase AIQuickGO ontologyBLASTP
42360394236482444DNA polymerase III chi subunitQuickGO ontologyBLASTP
423648242393372856valine tRNA synthetaseQuickGO ontologyBLASTP
42394664239642177putative IS1 encoded proteinQuickGO ontologyBLASTP
42397354240238504IS1 ORF2QuickGO ontologyBLASTP
424017342411921020hypothetical proteinBLASTP
42411944241697504IS1 ORF2QuickGO ontologyBLASTP
42418114242452642hypothetical proteinBLASTP
424252442435281005ornithine carbamoyltransferase 1QuickGO ontologyBLASTP
42436904244106417hypothetical proteinBLASTP
42442594244654396putative acetyltransferaseQuickGO ontologyBLASTP
42448204245065246hypothetical proteinBLASTP
42449854245218234putative IS1 encoded proteinQuickGO ontologyBLASTP
42452934245796504IS1 ORF2QuickGO ontologyBLASTP
42460404246963924hypothetical proteinBLASTP
42470864247547462hypothetical proteinBLASTP
42476834247937255hypothetical proteinBLASTP
42480094248173165hypothetical protein
42483474249060714putative oxidoreductaseQuickGO ontologyBLASTP
42491914249586396hypothetical proteinBLASTP
42498664250000135pyrBI operon leader peptideQuickGO ontologyBLASTP
42500044250939936aspartate carbamoyltransferase catalytic subunitQuickGO ontologyBLASTP
42509524251413462aspartate carbamoyltransferase regulatory subunitQuickGO ontologyBLASTP
42514474251872426hypothetical proteinBLASTP
425207842547742697Mg2 transport ATPaseQuickGO ontologyBLASTP
42551534256118966treRQuickGO ontologyBLASTP