Pre_GI: BLASTP Hits

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Query: NC_009699:2017329:2026020 Clostridium botulinum F str. Langeland chromosome, complete genome

Start: 2026020, End: 2026607, Length: 588

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum F strain Langeland was identified in 1958 from home-prepared liver paste involved in an outbreak of foodborne botulism on the island of Langeland, in Denmark. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:2017000:202612520261252026727603Clostridium botulinum F str. 230613 chromosome, complete genomephage major tail protein, phi13 family3e-108390
NC_010520:1614333:164439916443991644980582Clostridium botulinum A3 str. Loch Maree, complete genomephage major tail protein, Phi13 family subfamily9e-73272
NC_012563:2925472:293905829390582939639582Clostridium botulinum A2 str. Kyoto, complete genomephage major tail protein, Phi13 family1e-72272
NC_012563:2101449:211470421147042115285582Clostridium botulinum A2 str. Kyoto, complete genomephage major tail protein, Phi13 family5e-72270
NC_011773:4141765:415595841559584156563606Bacillus cereus AH820 chromosome, complete genomephage major tail protein, Phi13 family2e-22105
NC_014829:2915500:292259029225902923159570Bacillus cellulosilyticus DSM 2522 chromosome, complete genomephage major tail protein, phi13 family8e-21100
NC_014328:303063:373734373734374564831Clostridium ljungdahlii ATCC 49587 chromosome, complete genomephage protein6e-21100
NC_003030:2023751:203647320364732037393921Clostridium acetobutylicum ATCC 824, complete genomeUncharacterized phage related protein5e-21100
NC_015687:2025345:203806720380672038987921Clostridium acetobutylicum DSM 1731 chromosome, complete genomephage-like protein5e-21100
NC_017295:2022085:203588020358802036800921Clostridium acetobutylicum EA 2018 chromosome, complete genomehypothetical protein5e-21100
NC_013411:597235:620830620830621399570Geobacillus sp. Y412MC61, complete genomephage major tail protein, phi13 family6e-2097.1
NC_014915:2963500:298253629825362983105570Geobacillus sp. Y412MC52 chromosome, complete genomephage major tail protein, phi13 family6e-2097.1
NC_016935:1636278:166805216680521668666615Paenibacillus mucilaginosus 3016 chromosome, complete genomephage major tail protein, phi13 family2e-1995.9
NC_015690:1186545:121859012185901219219630Paenibacillus mucilaginosus KNP414 chromosome, complete genomephage major tail protein, phi13 family2e-1995.1
NC_006322:1507411:152341115234111523992582Bacillus licheniformis ATCC 14580, complete genomehypothetical protein9e-1993.2
NC_006270:1511000:152255015225501523131582Bacillus licheniformis ATCC 14580, complete genomephage related protein9e-1993.2
NC_015519:2489728:251513125151312515703573Tepidanaerobacter sp. Re1 chromosome, complete genomephage major tail protein, phi13 family8e-1890.1
NC_020291:1122282:113273611327361133314579Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomephage major tail protein, Phi13 family1e-1789.7
NC_017068:1216548:122138712213871221944558Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative phage major tail protein, phi13 family1e-1789.4
NC_014393:937000:967257967257967826570Clostridium cellulovorans 743B chromosome, complete genomephage major tail protein, phi13 family2e-1788.6
NC_014479:1961692:197064719706471971261615Bacillus subtilis subsp. spizizenii str. W23 chromosome, completehypothetical protein2e-1685.9
NC_021184:4493440:450408745040874504653567Desulfotomaculum gibsoniae DSM 7213, complete genomephage major tail protein, phi13 family3e-1581.6
NC_011658:2080390:208326720832672083851585Bacillus cereus AH187 chromosome, complete genomeputative prophage LambdaBa02, major tail protein3e-1581.6
NC_016771:2039195:204207220420722042656585Bacillus cereus NC7401, complete genomeprophage LambdaBa02, major tail protein3e-1581.6
NC_009697:3110772:312024131202413120840600Clostridium botulinum A str. ATCC 19397 chromosome, completephi13 family phage major tail protein7e-1580.5
NC_007530:3749645:376408837640883764672585Bacillus anthracis str. 'Ames Ancestor', complete genomeprophage lambdaba02, major tail protein, putative1e-1479.3
NC_005945:3747652:376446137644613765045585Bacillus anthracis str. Sterne, complete genomeprophage LambdaBa02, major tail protein, putative1e-1479.3
NC_003997:3724702:376396137639613764545585Bacillus anthracis str. Ames, complete genomeprophage LambdaBa02, major tail protein, putative1e-1479.3
NC_012581:466798:474145474145474729585Bacillus anthracis str. CDC 684 chromosome, complete genomeputative prophage LambdaBa02, major tail protein1e-1479.3
NC_012659:3724729:376398837639883764572585Bacillus anthracis str. A0248, complete genomeputative prophage LambdaBa02, major tail protein1e-1479.3
NC_009674:2678932:269186926918692692480612Bacillus cytotoxicus NVH 391-98 chromosome, complete genomephi13 family phage major tail protein2e-1272.4
NC_017068:1852708:188632018863201886916597Selenomonas ruminantium subsp. lactilytica TAM6421, completeputative phage major tail protein2e-1168.9
NC_017297:3428429:344109934410993441680582Clostridium botulinum F str. 230613 chromosome, complete genomephage major tail protein, phi13 family2e-1168.6
NC_009699:3429817:344248634424863443067582Clostridium botulinum F str. Langeland chromosome, complete genomephi13 family phage major tail protein2e-1168.6
NC_009697:2558286:257072925707292571310582Clostridium botulinum A str. ATCC 19397 chromosome, completephi13 family phage major tail protein4e-1167.8
NC_014624:1235818:125551912555191256106588Eubacterium limosum KIST612 chromosome, complete genomephage protein1e-1066.2
NC_010516:2676746:268921626892162689797582Clostridium botulinum B1 str. Okra, complete genomephage major tail protein, phi13 family2e-1065.5
NC_010674:950276:960411960411961010600Clostridium botulinum B str. Eklund 17B, complete genomemajor tail protein2e-0755.8
NC_006322:3418268:344534634453463445963618Bacillus licheniformis ATCC 14580, complete genomehypothetical protein2e-0755.8
NC_006270:3418097:344517534451753445792618Bacillus licheniformis ATCC 14580, complete genomeputative phagelike major tail protein2e-0755.8
NC_014538:1598106:161608216160821616684603Thermoanaerobacter sp. X513 chromosome, complete genomephage major tail protein, phi13 family1e-0653.1
NC_010320:1268355:129769712976971298299603Thermoanaerobacter sp. X514 chromosome, complete genomephi13 family phage major tail protein1e-0653.1
NC_014410:800500:820838820838821437600Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,phage major tail protein, phi13 family2e-0652.4
NC_016791:1341858:135313413531341353838705Clostridium sp. BNL1100 chromosome, complete genomephage major tail protein, phi13 family4e-0651.2
NC_018870:2316499:234275423427542343353600Thermacetogenium phaeum DSM 12270 chromosome, complete genomephage major tail protein, phi13 family5e-0650.8
NC_015520:2974048:298014729801472980746600Mahella australiensis 50-1 BON chromosome, complete genomephage major tail protein, phi13 family5e-0650.8