Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:2676746 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
26767462677666921hypothetical proteinBLASTP
26776862678351666hypothetical protein
26783442678832489hypothetical protein
26790512679242192hypothetical proteinBLASTP
26792442679603360putative chain A Sc Smc1hdScc1-C Complex AtpgsQuickGO ontology
267963126812711641hypothetical proteinBLASTP
26812782682156879hypothetical proteinBLASTP
26823492683215867putative phage tail proteinQuickGO ontologyBLASTP
268323226885925361phage related proteinQuickGO ontologyBLASTP
26888542689180327hypothetical proteinBLASTP
26892162689797582phage major tail protein phi13 familyQuickGO ontologyBLASTP
26898002690144345hypothetical proteinBLASTP
26901412690530390phage protein HK97 gp10 familyQuickGO ontologyBLASTP
26905232690849327putative phage head-tail adaptorQuickGO ontologyBLASTP
26908302691156327phage protein QLRG familyQuickGO ontologyBLASTP
269136926924961128putative phage capsid proteinQuickGO ontologyBLASTP
26924892693247759putative Clp proteaseQuickGO ontologyBLASTP
269323726944211185phage portal protein HK97 familyQuickGO ontologyBLASTP
269443726961371701putative phage terminase large subunitQuickGO ontologyBLASTP
26961342696598465phage terminase small subunit P27 familyQuickGO ontologyBLASTP
26968702697106237hypothetical protein
26971972697670474hypothetical proteinBLASTP
26976702698092423putative non-transporter ABC proteinQuickGO ontologyBLASTP
26981372698439303transglycosylaseQuickGO ontologyBLASTP
26986002699145546site-specific recombinase phage integrase familyQuickGO ontologyBLASTP
26991422699357216hypothetical proteinBLASTP
26995402699968429hypothetical protein
26999522700122171hypothetical proteinBLASTP
27001242700414291hypothetical protein
27005712701566996phage integraseQuickGO ontologyBLASTP
27017082701839132hypothetical proteinBLASTP
270193127029801050hypothetical proteinBLASTP
27030072703210204hypothetical proteinBLASTP
27032242703418195hypothetical proteinBLASTP
27034562703641186hypothetical proteinBLASTP
27036792704002324hypothetical proteinBLASTP
27040362704197162hypothetical protein
27042472704543297hypothetical protein
27045842705336753hypothetical proteinBLASTP
27053682705556189hypothetical protein
27055822705881300hypothetical protein
27058942706202309hypothetical protein
27062252706938714phage proteinQuickGO ontologyBLASTP
27069282707794867gp49 homologQuickGO ontologyBLASTP
27078322708104273hypothetical proteinBLASTP
27081212708303183hypothetical proteinBLASTP
27083052708565261hypothetical proteinBLASTP
27085772709377801phage proteinQuickGO ontologyBLASTP
27094772709593117hypothetical protein
27096312709753123hypothetical protein
27097312709934204putative DNA-binding proteinQuickGO ontology
27101402710505366putative DNA-binding proteinQuickGO ontologyBLASTP
271051727120311515resolvase family proteinQuickGO ontologyBLASTP
27120372712471435RNA polymerase sigma-K factorQuickGO ontologyBLASTP
27128972713076180hypothetical protein
27135212713658138hypothetical protein