Pre_GI: BLASTP Hits

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Query: NC_011896:3252925:3264850 Mycobacterium leprae Br4923, complete genome

Start: 3264850, End: 3265431, Length: 582

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_002677:3253057:326498232649823265563582Mycobacterium leprae TN, complete genomehypothetical protein2e-90330
NC_015564:4727630:473582747358274736336510Amycolicicoccus subflavus DQS3-9A1 chromosome, complete genomehypothetical protein2e-41168
NC_015953:3684065:369557636955763696085510Streptomyces sp. SirexAA-E chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein4e-32137
NC_016114:3655005:368074236807423681251510Streptomyces flavogriseus ATCC 33331 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein8e-32136
NC_018750:3964784:397616339761633976675513Streptomyces venezuelae ATCC 10712, complete genomeRNA-binding protein Jag6e-31133
NC_013929:5135285:514436951443695144881513Streptomyces scabiei 87.22 chromosome, complete genomenucleic-acid-binding protein Jag7e-31133
NC_003888:4251867:427534342753434275855513Streptomyces coelicolor A3(2), complete genomehypothetical protein1e-29129
NC_013595:10329633:103387611033876110339264504Streptosporangium roseum DSM 43021, complete genomespoIIIJ-associated protein3e-29127
NC_007333:3626510:363905136390513639590540Thermobifida fusca YX, complete genomesingle-stranded nucleic acid binding R3H3e-28124
NC_014210:5752651:576485457648545765342489Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,single-stranded nucleic acid binding R3H domain protein3e-28124
NC_008578:2431074:244059024405902441189600Acidothermus cellulolyticus 11B, complete genomesingle-stranded nucleic acid binding R3H domain protein2e-27122
NC_014151:4106624:412013541201354120647513Cellulomonas flavigena DSM 20109 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain protein2e-25115
NC_014039:2479500:249241224924122493023612Propionibacterium acnes SK137 chromosome, complete genomeR3H domain protein3e-25114
NC_016511:2482500:249570424957042496315612Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeR3H domain-containing protein3e-25114
NC_006085:2544421:255734725573472557958612Propionibacterium acnes KPA171202, complete genomeJAG-like protein3e-25114
NC_016516:2473500:248656124865612487172612Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeR3H domain-containing protein4e-25114
NC_016512:2506898:251982425198242520435612Propionibacterium acnes TypeIA2 P.acn17 chromosome, completeR3H domain-containing protein4e-25114
NC_014830:4012999:402108740210874021773687Intrasporangium calvum DSM 43043 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein5e-24110
NC_014550:3839389:385665538566553857182528Arthrobacter arilaitensis Re117, complete genomeR3H domain-containing protein2e-23108
NC_017093:8757291:877055787705578771126570Actinoplanes missouriensis 431, complete genomehypothetical protein6e-23107
NC_013521:4240468:425046442504644250988525Sanguibacter keddieii DSM 10542, complete genomepredicted RNA-binding protein1e-22106
NC_011886:4376261:439271143927114393277567Arthrobacter chlorophenolicus A6, complete genomesingle-stranded nucleic acid binding R3H domain protein3e-21101
NC_015145:4232283:424780242478024248368567Arthrobacter phenanthrenivorans Sphe3 chromosome, complete genomeRNA-binding protein6e-21100
NC_008541:4679022:469595046959504696516567Arthrobacter sp. FB24 chromosome 1, complete sequencesingle-stranded nucleic acid binding R3H domain protein4e-2097.8
NC_008711:4579997:459466045946604595211552Arthrobacter aurescens TC1, complete genomeputative jag-like protein4e-2097.4
NC_018531:4718904:473356947335694734120552Arthrobacter sp. Rue61a chromosome, complete genomejag-like protein5e-2097.4
NC_011593:2819230:283013828301382830671534Bifidobacterium longum subsp. infantis ATCC 15697 chromosome,single-stranded nucleic acid binding R3H domain-containing protein2e-1891.7
NC_017219:2815225:282613928261392826672534Bifidobacterium longum subsp. infantis ATCC 15697, complete genomehypothetical protein2e-1891.7
NC_017221:2268276:227565722756572276190534Bifidobacterium longum subsp. longum KACC 91563 chromosome,hypothetical protein5e-1890.9
NC_004307:1620500:162805216280521628585534Bifidobacterium longum NCC2705, complete genomenarrowly conserved hypothetical protein with possible ssDNA binding domain5e-1890.9
NC_015052:2383865:239749323974932398026534Bifidobacterium longum subsp. infantis 157F, complete genomehypothetical protein5e-1890.9
NC_015067:2371428:238234523823452382878534Bifidobacterium longum subsp. longum JCM 1217, complete genomehypothetical protein5e-1890.9
NC_014169:2466442:247522824752282475761534Bifidobacterium longum subsp. longum JDM301 chromosome, completesingle-stranded nucleic acid-binding R3H domain-containing protein5e-1890.9
NC_010816:1660066:166971816697181670251534Bifidobacterium longum DJO10A, complete genomeHypothetical RNA-binding protein1e-1789.7
NC_017218:2313245:232474623247462325282537Bifidobacterium breve ACS-071-V-Sch8b chromosome, complete genomeR3H domain-containing protein1e-1789.4
NC_018720:2138180:216415321641532164794642Bifidobacterium asteroides PRL2011 chromosome, complete genomer3H domain-containing protein2e-1789
NC_014656:1634397:164405016440501644583534Bifidobacterium longum subsp. longum BBMN68 chromosome, completejag2e-1788.6
NC_015389:2101841:211332221133222113900579Coriobacterium glomerans PW2 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein4e-1787.8
NC_014638:2199799:221184722118472212377531Bifidobacterium bifidum PRL2010 chromosome, complete genomehypothetical protein5e-1787.4
NC_014616:2172025:218407221840722184602531Bifidobacterium bifidum S17 chromosome, complete genomer3H domain-containing protein1e-1686.3
NC_006177:3549467:356356735635673564184618Symbiobacterium thermophilum IAM 14863, complete genomeSpoIIIJ-associated RNA-binding protein2e-1685.1
NC_016627:4871875:489516048951604895780621Clostridium clariflavum DSM 19732 chromosome, complete genomeputative RNA-binding protein2e-1685.1
NC_013204:3613824:362942936294293629950522Eggerthella lenta DSM 2243, complete genomesingle-stranded nucleic acid binding R3H domain protein5e-1684
NC_014833:3667748:368109336810933681908816Ruminococcus albus 7 chromosome, complete genomesingle-stranded nucleic acid-binding R3H domain-containing protein7e-1683.6
NC_004557:32094:544915449155138648Clostridium tetani E88, complete genomeconserved protein, JAG-family4e-1581.3
NC_013165:3146000:316135731613573161923567Slackia heliotrinireducens DSM 20476, complete genomepredicted RNA-binding protein1e-1479.7
NC_008593:2527064:190319032532630Clostridium novyi NT, complete genomeR3H domain protein2e-1479
NC_020134:2948000:297169629716962972334639Clostridium stercorarium subsp. stercorarium DSM 8532, completeprotein Jag5e-1477.4
NC_015387:1002955:101999210199921020588597Marinithermus hydrothermalis DSM 14884 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein3e-1375.1
NC_014392:2513529:252522525252252525851627Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein5e-1374.3
NC_015690:8645500:866105486610548661674621Paenibacillus mucilaginosus KNP414 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein5e-1373.9
NC_016935:8716704:873628387362838736903621Paenibacillus mucilaginosus 3016 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein5e-1373.9
NC_011898:4044500:406594340659434066575633Clostridium cellulolyticum H10, complete genomesingle-stranded nucleic acid binding R3H domain protein1e-1273.2
NC_015125:1597600:160667916066791607182504Microbacterium testaceum StLB037, complete genomepredicted RNA-binding protein1e-1273.2
NC_006448:1604627:1617490161749016185391050Streptococcus thermophilus LMG 18311, complete genomeconserved hypothetical protein, Jag protein3e-1271.6
NC_006449:1606948:1619801161980116208501050Streptococcus thermophilus CNRZ1066, complete genomeconserved hypothetical protein, Jag protein4e-1271.2
NC_016938:1830500:184343018434301844194765Melissococcus plutonius DAT561 chromosome 1, complete genomeRNA-binding protein Jag8e-1270.1
NC_015760:2009425:2024004202400420250471044Streptococcus salivarius CCHSS3, complete genomehypothetical protein1e-1169.7
NC_014220:2398334:240331324033132403942630Syntrophothermus lipocalidus DSM 12680 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain protein4e-1168.2
NC_013406:7092510:711237371123737113161789Paenibacillus sp. Y412MC10 chromosome, complete genomesingle-stranded nucleic acid-binding R3H domain-containing protein3e-1168.2
NC_015436:1:690469047611708Spirochaeta coccoides DSM 17374 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein7e-1167
NC_015519:2739347:275768227576822758296615Tepidanaerobacter sp. Re1 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein8e-1167
NC_014363:2035141:205038020503802050970591Olsenella uli DSM 7084 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain protein7e-0960.5
NC_009616:1604276:162034616203461621017672Thermosipho melanesiensis BI429 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain-containing protein1e-0859.7
NC_013192:2434664:246326224632622464083822Leptotrichia buccalis DSM 1135, complete genomesingle-stranded nucleic acid binding R3H domain protein2e-0858.9
NC_017243:314000:334078334078334782705Brachyspira intermedia PWS/A chromosome, complete genomejag protein2e-0755.8
NC_013522:736339:738824738824739519696Thermanaerovibrio acidaminovorans DSM 6589, complete genomesingle-stranded nucleic acid binding R3H domain protein2e-0755.5
NC_014221:398636:417296417296417877582Truepera radiovictrix DSM 17093 chromosome, complete genomesingle-stranded nucleic acid binding R3H domain protein1e-0653.1