Pre_GI Gene

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Host: NC_016516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016516:2473500 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
247368624750321347aminotransferaseQuickGO ontologyBLASTP
24753272476310984D-alanine--D-alanine ligaseQuickGO ontologyBLASTP
24762852477019735membrane-associated proteinQuickGO ontologyBLASTP
24770312477588558membrane-associated proteinQuickGO ontologyBLASTP
24778462478772927ParB-like proteinQuickGO ontologyBLASTP
24787692479755987CobQCobBMinDParA nucleotide binding domain-containing proteinQuickGO ontologyBLASTP
24813222481552231hypothetical proteinBLASTP
2481582248220862716S rRNA methyltransferase GidBQuickGO ontologyBLASTP
24826542482854201hypothetical proteinBLASTP
248419424852221029alanine racemaseQuickGO ontologyBLASTP
248522424863511128FemAB family proteinQuickGO ontologyBLASTP
24863602486557198hypothetical proteinBLASTP
24865612487172612R3H domain-containing proteinQuickGO ontologyBLASTP
248722524883041080putative inner membrane protein translocase component YidCQuickGO ontologyBLASTP
24887772489223447ribonuclease P protein componentQuickGO ontologyBLASTP
2489230248936413550S ribosomal protein L34QuickGO ontologyBLASTP