Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:2479500 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
24117431503chromosomal replication initiator protein DnaAQuickGO ontologyBLASTP
213133751245DNA polymerase III beta subunitQuickGO ontologyBLASTP
35124165654hypothetical proteinBLASTP
420254071206DNA recombination and repair protein RecFQuickGO ontologyBLASTP
54005993594hypothetical proteinBLASTP
60576731675hypothetical proteinBLASTP
648476171134hypothetical protein
830094871188mannose-6-phosphate isomerase class IQuickGO ontologyBLASTP
9729118012073DNA gyrase B subunitQuickGO ontologyBLASTP
247953724808831347aminotransferase class IIIQuickGO ontologyBLASTP
24812142482161948D-ala D-ala ligase N-terminal domain proteinQuickGO ontologyBLASTP
24821722482870699hypothetical proteinBLASTP
24828822483439558hypothetical proteinBLASTP
24836972484617921ParB-like proteinQuickGO ontologyBLASTP
24846202485606987CobQCobBMinDParA nucleotide binding domain proteinQuickGO ontologyBLASTP
24872662487403138hypothetical proteinBLASTP
2487433248805962716S rRNA methyltransferase GidBQuickGO ontologyBLASTP
24885052488660156hypothetical proteinBLASTP
249004524910731029alanine racemase N-terminal domain proteinQuickGO ontologyBLASTP
249107524922021128FemAB family proteinQuickGO ontologyBLASTP
24922112492408198hypothetical proteinBLASTP
24924122493023612R3H domain proteinQuickGO ontologyBLASTP
249307624941551080membrane protein insertase YidCOxa1 familyQuickGO ontologyBLASTP
24941552494352198hypothetical proteinBLASTP
24946282495074447ribonuclease P protein componentQuickGO ontologyBLASTP
24950812495215135ribosomal protein L34QuickGO ontologyBLASTP