Pre_GI Gene

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Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:2544421 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
24517471503chromosomal replication initiator protein DnaAQuickGO ontologyBLASTP
186833791512DNA polymerase III subunit betaQuickGO ontologyBLASTP
36664169504hypothetical proteinBLASTP
422754111185recombination protein FQuickGO ontologyBLASTP
53895997609hypothetical proteinBLASTP
830494911188mannose-6-phosphate isomeraseQuickGO ontologyBLASTP
9733118052073DNA topoisomerase IV subunit BQuickGO ontologyBLASTP
254442125458181398probable aminotransferaseQuickGO ontologyBLASTP
25461132547096984D-alanine--D-alanine ligase BQuickGO ontologyBLASTP
25470712547805735conserved membrane-associated proteinQuickGO ontologyBLASTP
25478022548374573conserved membrane-associated proteinQuickGO ontologyBLASTP
25486322549552921probable chromosome partitioning protein ParBQuickGO ontologyBLASTP
25495552550541987chromosome partitioning protein ParAQuickGO ontologyBLASTP
25506032550824222hypothetical protein
25509282551158231hypothetical protein
25517462552111366hypothetical protein
25521082552338231hypothetical proteinBLASTP
25523682552994627glucose-inhibited division protein BQuickGO ontologyBLASTP
25534402553640201hypothetical proteinBLASTP
25536462554032387hypothetical protein
25543072554750444hypothetical protein
255498025560081029putative alanine racemaseQuickGO ontologyBLASTP
255601025571011092FemAB family proteinQuickGO ontologyBLASTP
25571462557343198hypothetical proteinBLASTP
25573472557958612JAG-like proteinQuickGO ontologyBLASTP
255801125590901080putative inner membrane protein translocase component YidCQuickGO ontologyBLASTP
25590902559593504hypothetical proteinBLASTP
25595632559820258ribonuclease P protein componentQuickGO ontologyBLASTP
2560016256015013550S ribosomal protein L34QuickGO ontologyBLASTP