Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:2482500 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
248277824841751398aminotransferaseQuickGO ontologyBLASTP
24845062485453948D-alanine--D-alanine ligaseQuickGO ontologyBLASTP
24854462486162717membrane-associated proteinQuickGO ontologyBLASTP
24861742486731558membrane-associated proteinQuickGO ontologyBLASTP
24869892487915927ParB-like proteinQuickGO ontologyBLASTP
24879122488898987CobQCobBMinDParA nucleotide binding domain-containing proteinQuickGO ontologyBLASTP
24904652490695231hypothetical proteinBLASTP
2490725249135162716S rRNA methyltransferase GidBQuickGO ontologyBLASTP
24917972491997201hypothetical proteinBLASTP
249333724943651029alanine racemaseQuickGO ontologyBLASTP
249436724954941128FemAB family proteinQuickGO ontologyBLASTP
24955032495700198hypothetical proteinBLASTP
24957042496315612R3H domain-containing proteinQuickGO ontologyBLASTP
249636824974471080putative inner membrane protein translocase component YidCQuickGO ontologyBLASTP
24979202498366447ribonuclease P protein componentQuickGO ontologyBLASTP
2498373249850713550S ribosomal protein L34QuickGO ontologyBLASTP