Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:4251867 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
42518674252493627hypothetical proteinBLASTP
425285742578875031WD-40 repeat proteinQuickGO ontologyBLASTP
42582284258428201integral membrane proteinQuickGO ontology
42589934259403411decarboxylaseQuickGO ontologyBLASTP
42599794260536558integral membrane proteinQuickGO ontologyBLASTP
426074142633142574DNA gyrase subunit AQuickGO ontologyBLASTP
426337842654382061DNA topoisomerase IV subunit BQuickGO ontologyBLASTP
42658734266445573hypothetical proteinBLASTP
426644242675631122recombination protein FQuickGO ontologyBLASTP
426759442684698766-phosphogluconate dehydrogenaseQuickGO ontologyBLASTP
426871342698431131DNA polymerase III subunit betaQuickGO ontologyBLASTP
427077842727481971chromosomal replication initiator proteinQuickGO ontologyBLASTP
4273127427326413850S ribosomal protein L34QuickGO ontologyBLASTP
42732864273657372ribonuclease P componentQuickGO ontologyBLASTP
42736544274028375hypothetical proteinBLASTP
427403242753271296inner membrane protein translocase component YidCQuickGO ontologyBLASTP
42753434275855513hypothetical proteinBLASTP
42759804276699720glucose-inhibited division protein BQuickGO ontologyBLASTP
42772514278078828partitioning or sporulation proteinQuickGO ontologyBLASTP
42781954279181987partitioning or sporulation proteinQuickGO ontologyBLASTP
42795194280136618hypothetical proteinBLASTP
42802124280544333thioredoxinQuickGO ontologyBLASTP
42805834281551969thioredoxin reductase NADPHQuickGO ontologyBLASTP
42817114282559849hypothetical proteinBLASTP
42825774283287711RNA polymerase sigma-70 factorQuickGO ontologyBLASTP
428331642850071692hypothetical proteinBLASTP
428514742875822436transmembrane proteinQuickGO ontologyBLASTP
428762742899902364hypothetical proteinBLASTP
429021642916671452RNA nucleotidyltransferaseQuickGO ontologyBLASTP
42917644292357594hypothetical proteinBLASTP
429238942936661278hypothetical proteinBLASTP
429374642948281083hypothetical proteinBLASTP
42948734295550678hypothetical proteinBLASTP
429621542986022388secreted penicillin-binding proteinQuickGO ontologyBLASTP
429872343002311509integral membrane proteinQuickGO ontologyBLASTP
430030943013401032hypothetical proteinBLASTP
430140243025231122hypothetical proteinBLASTP
43026614302966306hypothetical proteinBLASTP
4303242430353229130S ribosomal protein S6QuickGO ontologyBLASTP
43036134304212600single-strand DNA-binding proteinQuickGO ontologyBLASTP
4304258430449423730S ribosomal protein S18QuickGO ontologyBLASTP
4304513430495944750S ribosomal protein L9QuickGO ontologyBLASTP
430506043064061347hypothetical proteinBLASTP