Pre_GI Gene

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Host: NC_016512 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016512:2506898 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
250689825082951398aminotransferaseQuickGO ontologyBLASTP
25086262509573948D-alanine--D-alanine ligaseQuickGO ontologyBLASTP
25095482510282735membrane-associated proteinQuickGO ontologyBLASTP
25102792510851573membrane-associated proteinQuickGO ontologyBLASTP
25111092512035927ParB-like proteinQuickGO ontologyBLASTP
25120322513018987CobQCobBMinDParA nucleotide binding domain-containing proteinQuickGO ontologyBLASTP
25145852514815231hypothetical proteinBLASTP
2514845251547162716S rRNA methyltransferase GidBQuickGO ontologyBLASTP
25159172516117201hypothetical proteinBLASTP
251745725184851029alanine racemaseQuickGO ontologyBLASTP
251848725196141128FemAB family proteinQuickGO ontologyBLASTP
25196232519820198hypothetical proteinBLASTP
25198242520435612R3H domain-containing proteinQuickGO ontologyBLASTP
252048825215671080putative inner membrane protein translocase component YidCQuickGO ontologyBLASTP
25220402522486447ribonuclease P protein componentQuickGO ontologyBLASTP
2522493252262713550S ribosomal protein L34QuickGO ontologyBLASTP