Pre_GI: BLASTP Hits

Some Help

Query: NC_008261:2770468:2790232 Clostridium perfringens ATCC 13124, complete genome

Start: 2790232, End: 2790702, Length: 471

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: The species type strain, originally isolated from a human gas gangrene patient. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_008262:2433979:245245524524552452925471Clostridium perfringens SM101, complete genomeSer/Thr protein phosphatase family protein1e-83307
NC_017297:3546467:355681535568153557285471Clostridium botulinum F str. 230613 chromosome, complete genomephosphodiesterase2e-30131
NC_010520:3526883:354208935420893542559471Clostridium botulinum A3 str. Loch Maree, complete genomephosphodiesterase, MJ0936 family3e-30130
NC_010321:1703000:171761917176191718119501Thermoanaerobacter pseudethanolicus ATCC 33223 chromosome, completephosphodiesterase2e-29127
NC_014964:1695000:170983217098321710332501Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, completephosphodiesterase2e-29127
NC_010674:426256:431098431098431577480Clostridium botulinum B str. Eklund 17B, complete genomephosphodiesterase, family5e-29126
NC_010723:420025:424843424843425322480Clostridium botulinum E3 str. Alaska E43, complete genomephosphodiesterase, family2e-27121
NC_018870:427357:429726429726430199474Thermacetogenium phaeum DSM 12270 chromosome, complete genomephosphodiesterase YfcE5e-1993.6
NC_006270:2850354:286549628654962866017522Bacillus licheniformis ATCC 14580, complete genomehypothetical protein7e-1889.7
NC_006322:2851215:286635728663572866878522Bacillus licheniformis ATCC 14580, complete genomeYsnB7e-1889.7
NC_009483:2640403:264893226489322649402471Geobacter uraniireducens Rf4 chromosome, complete genomephosphodiesterase3e-1787.4
NC_012659:4273606:428778942877894288292504Bacillus anthracis str. A0248, complete genomeputative phosphoesterase5e-1683.2
NC_003997:4273579:428776242877624288265504Bacillus anthracis str. Ames, complete genomephosphoesterase, putative5e-1683.2
NC_014335:4181710:422152342215234222026504Bacillus cereus biovar anthracis str. CI chromosome, completeputative phosphoesterase5e-1683.2
NC_013315:3689422:370043837004383700908471Clostridium difficile CD196 chromosome, complete genomephosphoesterase6e-1683.2
NC_003454:618290:633341633341633802462Fusobacterium nucleatum subsp. nucleatum ATCC 25586, completeHypothetical protein with Metallo-phosphoesterase motif7e-1682.8
NC_014171:4317520:434859343485934349096504Bacillus thuringiensis BMB171 chromosome, complete genomephosphoesterase9e-1682.4
NC_017208:4435573:448007244800724480575504Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeputative phosphoesterase9e-1682.4
NC_012778:403962:421716421716422219504Eubacterium eligens ATCC 27750, complete genomehypothetical protein1e-1582
NC_012472:4255729:429325142932514293754504Bacillus cereus 03BB102, complete genomeputative phosphoesterase2e-1581.3
NC_015873:1933036:195454319545431955049507Megasphaera elsdenii DSM 20460, complete genomephosphodiesterase5e-1580.1
NC_013791:579842:594061594061594573513Bacillus pseudofirmus OF4 chromosome, complete genomehypothetical protein5e-1476.6
NC_008555:1204000:120689112068911207415525Listeria welshimeri serovar 6b str. SLCC5334, complete genomephosphoesterase family protein7e-1476.3
NC_011661:1100576:110651411065141107056543Dictyoglomus turgidum DSM 6724, complete genomephosphodiesterase, MJ0936 family3e-1270.9
NC_021171:2562000:256422525642252564773549Bacillus sp. 1NLA3E, complete genomephosphodiesterase3e-1270.9
NC_015732:529201:542929542929543486558Spirochaeta caldaria DSM 7334 chromosome, complete genomephosphodiesterase9e-1269.3
NC_004557:2475030:249379924937992494302504Clostridium tetani E88, complete genomeputative phosphoesterase7e-1166.2
NC_013192:2434664:245497924549792455431453Leptotrichia buccalis DSM 1135, complete genomephosphodiesterase, MJ0936 family2e-1064.7
NC_014209:761832:769761769761770303543Thermoanaerobacter mathranii subsp. mathranii str. A3 chromosome,phosphodiesterase, MJ0936 family6e-1063.2
NC_007168:1839382:185616518561651856674510Staphylococcus haemolyticus JCSC1435, complete genomehypothetical protein2e-0961.6
NC_009515:474285:479450479450479989540Methanobrevibacter smithii ATCC 35061, complete genomephosphoesterase, YfcE3e-0960.8
NC_012779:2586175:260189026018902602453564Edwardsiella ictaluri 93-146, complete genomehypothetical protein7e-0959.7
NC_012883:1421644:143847114384711438998528Thermococcus sibiricus MM 739, complete genomeMetallophosphoesterase, calcineurin superfamily1e-0858.5
NC_010520:1146000:115554911555491156094546Clostridium botulinum A3 str. Loch Maree, complete genomephosphodiesterase, MJ0936 family3e-0857.8
NC_012658:1052957:106015510601551060700546Clostridium botulinum Ba4 str. 657 chromosome, complete genomephosphodiesterase4e-0857
NC_014393:2905248:291783429178342918331498Clostridium cellulovorans 743B chromosome, complete genomephosphodiesterase, MJ0936 family6e-0856.6
NC_009465:90000:108746108746109228483Candidatus Vesicomyosocius okutanii HA, complete genomehypothetical protein7e-0856.2
NC_014029:3245778:326616232661623266713552Yersinia pestis Z176003 chromosome, complete genomehypothetical protein1e-0755.8
NC_009698:3275839:329107832910783291542465Clostridium botulinum A str. Hall chromosome, complete genomephosphodiesterase5e-0753.5
NC_000909:858840:865544865544866044501Methanocaldococcus jannaschii DSM 2661, complete genomehypothetical protein9e-0752.8
NC_010516:3466000:348629734862973486761465Clostridium botulinum B1 str. Okra, complete genomephosphodiesterase, MJ0936 family2e-0652
NC_018870:1417851:142244514224451423008564Thermacetogenium phaeum DSM 12270 chromosome, complete genomeputative phosphodiesterase YfcE2e-0651.6
NC_015416:2692536:269728626972862697831546Methanosaeta concilii GP-6 chromosome, complete genomephosphoesterase2e-0651.2