Pre_GI Gene

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Host: NC_010520 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010520:3526883 Clostridium botulinum A3 str. Loch Maree, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A3 str. Loch Maree was isolated from duck liver paste during a botulism outbreak at a hotel in the Scottish highlands in 1922. This was the first and worst outbreak of botulism in the United Kingdom (UK). This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
352688335280731191dihydroorotase multifunctional complex typeQuickGO ontologyBLASTP
35280953528535441aspartate carbamoyltransferase regulatory subunitQuickGO ontologyBLASTP
35285373529460924aspartate carbamoyltransferaseQuickGO ontologyBLASTP
35297153530473759putative CoA-substrate-specific enzyme activaseQuickGO ontologyBLASTP
35304963530747252hypothetical proteinBLASTP
353107535323341260putative R-2-hydroxyglutaryl-CoA dehydratase subunitQuickGO ontologyBLASTP
353246335336111149putative R-2-hydroxyglutaryl-CoA dehydratase subunitQuickGO ontologyBLASTP
35337233534055333hypothetical proteinBLASTP
35341013534850750ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
35348503534987138hypothetical proteinBLASTP
35350273535569543ABC transporter permease proteinQuickGO ontologyBLASTP
35356173536153537hypothetical proteinBLASTP
35362053536423219hypothetical proteinBLASTP
353643035375301101putative lipoproteinQuickGO ontologyBLASTP
35375483538012465putative lipoproteinQuickGO ontologyBLASTP
353802835391191092putative permeaseQuickGO ontologyBLASTP
35391193539379261hypothetical proteinBLASTP
35395353539765231sodiumdicarboxylate symporter family proteinQuickGO ontologyBLASTP
3539919353999577tRNA-ArgQuickGO ontology
3540021354009474tRNA-GlyQuickGO ontology
3540123354020078tRNA-ProQuickGO ontologyBLASTP
3540226354030176tRNA-LysQuickGO ontology
3540306354038479tRNA-ArgQuickGO ontologyBLASTP
3540390354046374tRNA-GlyQuickGO ontology
3540472354054675tRNA-GlyQuickGO ontology
3540620354070586tRNA-LeuQuickGO ontology
3540719354079678tRNA-LysQuickGO ontologyBLASTP
3540798354087477tRNA-GlnQuickGO ontologyBLASTP
3540877354095478tRNA-HisQuickGO ontologyBLASTP
3540969354104476tRNA-LysQuickGO ontology
3541049354112779tRNA-ArgQuickGO ontologyBLASTP
3541133354120674tRNA-GlyQuickGO ontology
3541215354128975tRNA-GlyQuickGO ontology
3541363354144886tRNA-LeuQuickGO ontology
3541462354153978tRNA-LysQuickGO ontologyBLASTP
3541541354161777tRNA-GlnQuickGO ontologyBLASTP
3541620354169778tRNA-HisQuickGO ontologyBLASTP
3541703354178179tRNA-ArgQuickGO ontologyBLASTP
3541787354186074tRNA-GlyQuickGO ontology
3541867354194478tRNA-ProQuickGO ontologyBLASTP
35420893542559471phosphodiesterase MJ0936 familyQuickGO ontologyBLASTP
35425773543176600non-canonical purine NTP pyrophosphatase rdgBHAM1 familyQuickGO ontologyBLASTP
354328035446531374hypothetical proteinBLASTP
35447663544921156hypothetical proteinBLASTP
354492435464861563bacterial extracellular solute-binding protein family 5QuickGO ontologyBLASTP
354664035480701431glutamyl-tRNAGln amidotransferase B subunitQuickGO ontologyBLASTP
354810735495641458glutamyl-tRNAGln amidotransferase A subunitQuickGO ontologyBLASTP
35496013549888288glutamyl-tRNAGln amidotransferase C subunitQuickGO ontologyBLASTP
355002435512351212sodiumdicarboxylate symporter family proteinQuickGO ontologyBLASTP