Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4255729 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4255729425601929150S ribosomal protein L27QuickGO ontologyBLASTP
42560234256367345hypothetical proteinBLASTP
4256379425668730950S ribosomal protein L21QuickGO ontologyBLASTP
425685742582451389ribonuclease RneRng familyQuickGO ontologyBLASTP
42583134259173861stage IV sporulation protein FBQuickGO ontologyBLASTP
42591664259912747stage IV sporulation protein FAQuickGO ontologyBLASTP
42600464260843798septum site-determining protein MinDQuickGO ontologyBLASTP
42608464261532687septum site-determining protein MinCQuickGO ontologyBLASTP
42615684262113546rod shape-determining protein MreDQuickGO ontologyBLASTP
42621284262979852rod shape-determining protein MreCQuickGO ontologyBLASTP
426302142640401020rod shape-determining protein MreBQuickGO ontologyBLASTP
42641994264876678DNA repair protein RadCQuickGO ontologyBLASTP
42649234265498576septum formation protein MafQuickGO ontologyBLASTP
42657204266682963putative stage II sporulation protein BQuickGO ontologyBLASTP
426684842681491302tetrahydrofolylpolyglutamate synthasedihydrofolate synthaseQuickGO ontologyBLASTP
426824342708882646valyl-tRNA synthetaseQuickGO ontologyBLASTP
427128442723091026spore coat protein YsxEQuickGO ontologyBLASTP
42723724273355984stage VI sporulation protein DQuickGO ontologyBLASTP
427346542747541290glutamate-1-semialdehyde-21-aminomutaseQuickGO ontologyBLASTP
42747544275743990delta-aminolevulinic acid dehydrataseQuickGO ontologyBLASTP
42757644276516753uroporphyrinogen-III synthaseQuickGO ontologyBLASTP
42765194277448930porphobilinogen deaminaseQuickGO ontologyBLASTP
42774644278297834hemX proteinQuickGO ontologyBLASTP
427831542796491335glutamyl-tRNA reductaseQuickGO ontologyBLASTP
42800614280513453transcriptional regulator MarR familyQuickGO ontologyBLASTP
42805164280932417organic hydroperoxide resistance proteinQuickGO ontologyBLASTP
42809654281561597GTP-binding proteinQuickGO ontologyBLASTP
428155842838882331ATP-dependent protease La 1QuickGO ontologyBLASTP
428407242857451674ATP-dependent protease LonBQuickGO ontologyBLASTP
428584942871081260ATP-dependent Clp protease ATP-binding subunit ClpXQuickGO ontologyBLASTP
428737342886501278trigger factorQuickGO ontologyBLASTP
42889604289958999hypothetical proteinBLASTP
42901354290269135hypothetical protein
42906924291105414hypothetical proteinBLASTP
42912614291875615hypothetical proteinBLASTP
42919604292160201hypothetical proteinBLASTP
42924104292535126hypothetical proteinBLASTP
42931484293279132hypothetical proteinBLASTP
42932514293754504putative phosphoesteraseQuickGO ontologyBLASTP
42937664294374609non-canonical purine NTP pyrophosphatase RdgBHAM1 familyQuickGO ontologyBLASTP
42943864295123738ribonuclease PHQuickGO ontologyBLASTP
429525242963011050germination protein gerMQuickGO ontologyBLASTP