Query: NC_008262:2348328 Clostridium perfringens SM101, complete genome
Start: 2348328, End: 2367084, Length: 18757
Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_015424:4251369* | 4251369 | 4276273 | 24905 | Aeromonas veronii B565 chromosome, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014910:465980* | 465980 | 507765 | 41786 | Alicycliphilus denitrificans BC chromosome, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014829:3822125* | 3822125 | 3853836 | 31712 | Bacillus cellulosilyticus DSM 2522 chromosome, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_014932:985882* | 985882 | 1033911 | 48030 | Bartonella clarridgeiae 73, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_012846:825341* | 825341 | 843599 | 18259 | Bartonella grahamii as4aup, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_020301:669000* | 669000 | 711176 | 42177 | Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_010645:3720501* | 3720501 | 3745499 | 24999 | Bordetella avium 197N, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_002927:5327094* | 5327094 | 5353999 | 26906 | Bordetella bronchiseptica RB50, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014657:1775929* | 1775929 | 1796570 | 20642 | Caldicellulosiruptor owensensis OL chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_019814:125611* | 125611 | 173456 | 47846 | Candidatus Kinetoplastibacterium blastocrithidii (ex Strigomonas | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_020299:764526* | 764526 | 817499 | 52974 | Candidatus Kinetoplastibacterium oncopeltii TCC290E, complete | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_009465:766893* | 766893 | 800980 | 34088 | Candidatus Vesicomyosocius okutanii HA, complete genome | 4e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_010723:3395187* | 3395187 | 3430218 | 35032 | Clostridium botulinum E3 str. Alaska E43, complete genome | 2e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_011898:649000* | 649000 | 671397 | 22398 | Clostridium cellulolyticum H10, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014393:3494863 | 3494863 | 3518479 | 23617 | Clostridium cellulovorans 743B chromosome, complete genome | 1e-17 | 99.6 | BLASTN svg | BLASTP svg |
NC_014328:1596016* | 1596016 | 1614099 | 18084 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 9e-09 | 69.9 | BLASTN svg | BLASTP svg |
NC_021182:4367736* | 4367736 | 4390827 | 23092 | Clostridium pasteurianum BC1, complete genome | 4e-14 | 87.7 | BLASTN svg | BLASTP svg |
NC_021182:2965395 | 2965395 | 2988500 | 23106 | Clostridium pasteurianum BC1, complete genome | 8e-37 | 163 | BLASTN svg | BLASTP svg |
NC_008261:64678* | 64678 | 101248 | 36571 | Clostridium perfringens ATCC 13124, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_008262:101731* | 101731 | 125280 | 23550 | Clostridium perfringens SM101, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_008262:2242432 | 2242432 | 2266662 | 24231 | Clostridium perfringens SM101, complete genome | 2e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_003366:2356148 | 2356148 | 2381797 | 25650 | Clostridium perfringens str. 13, complete genome | 2e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_003366:64908* | 64908 | 113675 | 48768 | Clostridium perfringens str. 13, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_020291:795500* | 795500 | 854572 | 59073 | Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome | 3e-24 | 121 | BLASTN svg | BLASTP svg |
NC_020291:5808856 | 5808856 | 5852592 | 43737 | Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome | 1e-23 | 119 | BLASTN svg | BLASTP svg |
NC_010002:528529* | 528529 | 550034 | 21506 | Delftia acidovorans SPH-1, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014828:637523 | 637523 | 669611 | 32089 | Ethanoligenens harbinense YUAN-3 chromosome, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_012781:751757* | 751757 | 774134 | 22378 | Eubacterium rectale ATCC 33656, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_015696:105748* | 105748 | 129268 | 23521 | Francisella sp. TX077308 chromosome, complete genome | 9e-06 | 60 | BLASTN svg | BLASTP svg |
NC_003454:677699* | 677699 | 702244 | 24546 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete | 1e-23 | 119 | BLASTN svg | BLASTP svg |
NC_015318:1336282* | 1336282 | 1376041 | 39760 | Hippea maritima DSM 10411 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014759:3572500* | 3572500 | 3602009 | 29510 | Marivirga tractuosa DSM 4126 chromosome, complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_013009:608515* | 608515 | 629505 | 20991 | Neorickettsia risticii str. Illinois, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_007798:586500* | 586500 | 611673 | 25174 | Neorickettsia sennetsu str. Miyayama, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_015458:3077804* | 3077804 | 3100903 | 23100 | Pusillimonas sp. T7-7 chromosome, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015437:918614* | 918614 | 942728 | 24115 | Selenomonas sputigena ATCC 35185 chromosome, complete genome | 2e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_012121:1444633* | 1444633 | 1468841 | 24209 | Staphylococcus carnosus subsp. carnosus TM300, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_003155:5957657* | 5957657 | 5981162 | 23506 | Streptomyces avermitilis MA-4680, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_003888:5042283* | 5042283 | 5087561 | 45279 | Streptomyces coelicolor A3(2), complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_021177:4912982* | 4912982 | 4935625 | 22644 | Streptomyces fulvissimus DSM 40593, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_010572:3363830* | 3363830 | 3421214 | 57385 | Streptomyces griseus subsp. griseus NBRC 13350, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_015957:639774* | 639774 | 666502 | 26729 | Streptomyces violaceusniger Tu 4113 chromosome, complete genome | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_006177:2943259* | 2943259 | 2965942 | 22684 | Symbiobacterium thermophilum IAM 14863, complete genome | 2e-16 | 95.6 | BLASTN svg | BLASTP svg |
NC_014410:2149886* | 2149886 | 2172209 | 22324 | Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome, | 1e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_019970:2190695* | 2190695 | 2211150 | 20456 | Thermoanaerobacterium thermosaccharolyticum M0795, complete genome | 4e-11 | 77.8 | BLASTN svg | BLASTP svg |
NC_015555:693461* | 693461 | 716445 | 22985 | Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete | 1e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_013520:1559000* | 1559000 | 1580886 | 21887 | Veillonella parvula DSM 2008, complete genome | 2e-28 | 135 | BLASTN svg | BLASTP svg |