Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:5042283 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
50422835043134852hypothetical proteinBLASTP
50432245043691468integral membrane proteinQuickGO ontologyBLASTP
504386550459102046sporulation-related proteinQuickGO ontologyBLASTP
50459255046464540sporulation-related proteinQuickGO ontologyBLASTP
50464845046984501integral membrane proteinQuickGO ontologyBLASTP
50470125047170159hypothetical protein
50473285047663336hypothetical proteinBLASTP
504766350486701008hypothetical proteinBLASTP
50486675049200534hypothetical protein
50491975049466270hypothetical proteinBLASTP
50498935050702810regulatorQuickGO ontologyBLASTP
50506995051364666hypothetical proteinBLASTP
505146550527241260hypothetical protein
505298450546661683hypothetical proteinBLASTP
505582850587282901ATPGTP binding proteinQuickGO ontologyBLASTP
50590255059681657hypothetical proteinBLASTP
505978650610901305hydrolaseQuickGO ontologyBLASTP
5061316506138873tRNA-ThrQuickGO ontologyBLASTP
5061435506150773tRNA-MetQuickGO ontologyBLASTP
5061599506176316550S ribosomal protein L33QuickGO ontologyBLASTP
50618595062311453hypothetical proteinBLASTP
50623175062745429hypothetical proteinBLASTP
50628455063669825hypothetical proteinBLASTP
50637345064339606hypothetical proteinBLASTP
50644055064998594tetR-family transcriptional regulatorQuickGO ontologyBLASTP
506511450665861473transmembrane efflux proteinQuickGO ontologyBLASTP
50666245067004381hypothetical proteinBLASTP
506700150681521152UDP-N-acetylenolpyruvoylglucosamine reductaseQuickGO ontologyBLASTP
506859250696231032adenosine deaminaseQuickGO ontologyBLASTP
506974950709751227aspartate aminotransferaseQuickGO ontologyBLASTP
5071215507129076tRNA-TrpQuickGO ontologyBLASTP
50713965071680285preprotein translocase SecE subunitQuickGO ontologyBLASTP
50717615072663903transcription antitermination proteinQuickGO ontologyBLASTP
5072851507328543550S ribosomal protein L11QuickGO ontologyBLASTP
5073369507409472650S ribosomal protein L1QuickGO ontologyBLASTP
50742675075124858lipoproteinQuickGO ontologyBLASTP
50752735076121849lipoproteinQuickGO ontologyBLASTP
5076440507697053150S ribosomal protein L10QuickGO ontologyBLASTP
5077088507747138450S ribosomal protein L7L12QuickGO ontologyBLASTP
507806150815463486DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
508164450855433900DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
50856535086240588integral membrane proteinQuickGO ontology
508625750875611305integral membrane proteinQuickGO ontologyBLASTP