Pre_GI: BLASTN Hits

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Query: NC_008262:2348328 Clostridium perfringens SM101, complete genome

Start: 2348328, End: 2367084, Length: 18757

Host Lineage: Clostridium perfringens; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This is a enterotoxin-producing food poisoning strain. Causative agent of gas gangrene. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a causative agent of a wide spectrum of necrotic enterotoxicoses. It also causes such animal diseases as lamb dysentery, ovine enterotoxemia (struck), pulpy kidney disease in lambs and other enterotoxemias in lambs and calves. It is commonly found in the environment (soil, sewage) and in the animal and human gastrointestinal tract as a member of the normal microflora. It is a fast growing (generation time 8-10 min) anaerobic flesh-eater. Active fermentative growth is accompanied by profuse generation of molecular hydrogen and carbon dioxide. It is also oxygen tolerant which makes it an easy object to work with in laboratories. C. perfringens have been developed and the species became a model organism in clostridial genetic studies. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. Known isolates belong to five distinct types (A, B, C, D, and E) that are distinguished based on the specific extracellular toxins they produce. All types produce the alpha toxin (phospholipase C). Type A strains that cause gas gangrene produce alpha toxin, theta (hemolysin), kappa (collagenase), mu (hyaluronidase), nu (DNAse) and neuraminidase which are all the enzymatic factors aiding the bacterium in invading and destruction of the host tissues. Type C strains produce alpha toxin, beta toxin and prefringolysin enteritis. In addition to alpha toxin, Type B strains produce beta toxin, types B and D produce the pore forming epsilon toxin and type E strains produce iota toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_021182:29653952965395298850023106Clostridium pasteurianum BC1, complete genome8e-37163BLASTN svgBLASTP svg
NC_013520:1559000*1559000158088621887Veillonella parvula DSM 2008, complete genome2e-28135BLASTN svgBLASTP svg
NC_020291:795500*79550085457259073Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-24121BLASTN svgBLASTP svg
NC_020291:58088565808856585259243737Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome1e-23119BLASTN svgBLASTP svg
NC_003454:677699*67769970224424546Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete1e-23119BLASTN svgBLASTP svg
NC_014393:34948633494863351847923617Clostridium cellulovorans 743B chromosome, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_006177:2943259*2943259296594222684Symbiobacterium thermophilum IAM 14863, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_008262:22424322242432226666224231Clostridium perfringens SM101, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_003366:23561482356148238179725650Clostridium perfringens str. 13, complete genome2e-1591.7BLASTN svgBLASTP svg
NC_014759:3572500*3572500360200929510Marivirga tractuosa DSM 4126 chromosome, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_021182:4367736*4367736439082723092Clostridium pasteurianum BC1, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_009465:766893*76689380098034088Candidatus Vesicomyosocius okutanii HA, complete genome4e-1487.7BLASTN svgBLASTP svg
NC_015437:918614*91861494272824115Selenomonas sputigena ATCC 35185 chromosome, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_019970:2190695*2190695221115020456Thermoanaerobacterium thermosaccharolyticum M0795, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_014410:2149886*2149886217220922324Thermoanaerobacterium thermosaccharolyticum DSM 571 chromosome,1e-1075.8BLASTN svgBLASTP svg
NC_012781:751757*75175777413422378Eubacterium rectale ATCC 33656, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_010723:3395187*3395187343021835032Clostridium botulinum E3 str. Alaska E43, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_012846:825341*82534184359918259Bartonella grahamii as4aup, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_014328:1596016*1596016161409918084Clostridium ljungdahlii ATCC 49587 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_019814:125611*12561117345647846Candidatus Kinetoplastibacterium blastocrithidii (ex Strigomonas9e-0969.9BLASTN svgBLASTP svg
NC_020299:764526*76452681749952974Candidatus Kinetoplastibacterium oncopeltii TCC290E, complete9e-0969.9BLASTN svgBLASTP svg
NC_011898:649000*64900067139722398Clostridium cellulolyticum H10, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_003155:5957657*5957657598116223506Streptomyces avermitilis MA-4680, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_003366:64908*6490811367548768Clostridium perfringens str. 13, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_003888:5042283*5042283508756145279Streptomyces coelicolor A3(2), complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008261:64678*6467810124836571Clostridium perfringens ATCC 13124, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008262:101731*10173112528023550Clostridium perfringens SM101, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_010572:3363830*3363830342121457385Streptomyces griseus subsp. griseus NBRC 13350, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014829:3822125*3822125385383631712Bacillus cellulosilyticus DSM 2522 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014932:985882*985882103391148030Bartonella clarridgeiae 73, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_015555:693461*69346171644522985Thermoanaerobacterium xylanolyticum LX-11 chromosome, complete1e-0765.9BLASTN svgBLASTP svg
NC_015957:639774*63977466650226729Streptomyces violaceusniger Tu 4113 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_021177:4912982*4912982493562522644Streptomyces fulvissimus DSM 40593, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_002927:5327094*5327094535399926906Bordetella bronchiseptica RB50, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_010002:528529*52852955003421506Delftia acidovorans SPH-1, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_010645:3720501*3720501374549924999Bordetella avium 197N, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014910:465980*46598050776541786Alicycliphilus denitrificans BC chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015424:4251369*4251369427627324905Aeromonas veronii B565 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015458:3077804*3077804310090323100Pusillimonas sp. T7-7 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_007798:586500*58650061167325174Neorickettsia sennetsu str. Miyayama, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_012121:1444633*1444633146884124209Staphylococcus carnosus subsp. carnosus TM300, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_013009:608515*60851562950520991Neorickettsia risticii str. Illinois, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_014657:1775929*1775929179657020642Caldicellulosiruptor owensensis OL chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015318:1336282*1336282137604139760Hippea maritima DSM 10411 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_020301:669000*66900071117642177Bartonella vinsonii subsp. berkhoffii str. Winnie, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_015696:105748*10574812926823521Francisella sp. TX077308 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014828:63752363752366961132089Ethanoligenens harbinense YUAN-3 chromosome, complete genome9e-0660BLASTN svgBLASTP svg