Pre_GI Gene

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Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:5957657 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
59576575958085429hypothetical proteinBLASTP
59583105958879570TetR-family transcriptional regulatorQuickGO ontologyBLASTP
595899359604621470transmembrane efflux proteinQuickGO ontologyBLASTP
596056859616621095UDP-N-acetylenolpyruvoylglucosamine reductaseQuickGO ontologyBLASTP
596186059628881029adenosine deaminaseQuickGO ontologyBLASTP
596305659642821227aspartate aminotransferaseQuickGO ontologyBLASTP
5964532596460776tRNA-TrpQuickGO ontologyBLASTP
59647125964999288preprotein translocaseQuickGO ontologyBLASTP
59650775965940864transcription antitermination proteinQuickGO ontologyBLASTP
59661115966545435ribosomal protein L11QuickGO ontologyBLASTP
5966625596735072650S ribosomal protein L1QuickGO ontologyBLASTP
5967982596851253150S ribosomal protein L10QuickGO ontologyBLASTP
59686225969005384ribosomal protein L7L12QuickGO ontologyBLASTP
596956859731133546DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
597322459771233900DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
59771605977861702hypothetical proteinBLASTP
5978149597852037230S ribosomal protein S12QuickGO ontologyBLASTP
5978523597899347130S ribosomal protein S7QuickGO ontologyBLASTP
597903359811622130translation elongation factor GQuickGO ontologyBLASTP