Pre_GI: BLASTN Hits

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Query: NC_009698:3006500 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 3006500, End: 3025591, Length: 19092

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_012563:3374904*3374904339859023687Clostridium botulinum A2 str. Kyoto, complete genome03907BLASTN svgBLASTP svg
NC_010520:3204480*3204480322378019301Clostridium botulinum A3 str. Loch Maree, complete genome03152BLASTN svgBLASTP svg
NC_010516:3196158*3196158321545819301Clostridium botulinum B1 str. Okra, complete genome03120BLASTN svgBLASTP svg
NC_008593:1704207*1704207172452320317Clostridium novyi NT, complete genome0805BLASTN svgBLASTP svg
NC_020291:1014333*1014333103759923267Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome0704BLASTN svgBLASTP svg
NC_008261:2524913*2524913254259917687Clostridium perfringens ATCC 13124, complete genome0646BLASTN svgBLASTP svg
NC_021182:2192718*2192718221646323746Clostridium pasteurianum BC1, complete genome2e-139504BLASTN svgBLASTP svg
NC_003869:94800094800097076722768Thermoanaerobacter tengcongensis MB4, complete genome3e-27131BLASTN svgBLASTP svg
NC_013454:229587*22958725413424548Blattabacterium sp. (Blattella germanica) str. Bge, complete2e-25125BLASTN svgBLASTP svg
NC_007622:1558753*1558753157743218680Staphylococcus aureus RF122, complete genome4e-20107BLASTN svgBLASTP svg
NC_016012:879972*87997290262722656Candidatus Arthromitus sp. SFB-rat-Yit, complete genome2e-19105BLASTN svgBLASTP svg
NC_014393:1782811*1782811180519922389Clostridium cellulovorans 743B chromosome, complete genome3e-18101BLASTN svgBLASTP svg
NC_010001:2836995*2836995286257025576Clostridium phytofermentans ISDg, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_020291:18105271810527182940518879Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome3e-1591.7BLASTN svgBLASTP svg
NC_012225:236490*23649025991523426Brachyspira hyodysenteriae WA1, complete genome6e-1383.8BLASTN svgBLASTP svg
NC_005957:4104880*4104880412588721008Bacillus thuringiensis serovar konkukian str. 97-27, complete2e-1281.8BLASTN svgBLASTP svg
NC_005945:4116978*4116978413524218265Bacillus anthracis str. Sterne, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_004722:4244730*4244730426728722558Bacillus cereus ATCC 14579, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_003997:4116944*4116944413809921156Bacillus anthracis str. Ames, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_003909:4064904*4064904408337118468Bacillus cereus ATCC 10987, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_006274:4159096*4159096417709918004Bacillus cereus E33L, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_007530:4117071*4117071413809921029Bacillus anthracis str. 'Ames Ancestor', complete genome2e-1281.8BLASTN svgBLASTP svg
NC_008600:4101748*4101748412497023223Bacillus thuringiensis str. Al Hakam, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_010184:4155345*4155345417709921755Bacillus weihenstephanensis KBAB4, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_011772:4255161*4255161427769522535Bacillus cereus G9842, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_012472:4119192*4119192414241423223Bacillus cereus 03BB102, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_014150:1*11978219782Brachyspira murdochii DSM 12563 chromosome, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_014335:4027105*4027105404657819474Bacillus cereus biovar anthracis str. CI chromosome, complete2e-1281.8BLASTN svgBLASTP svg
NC_013515:14834711483471150341619946Streptobacillus moniliformis DSM 12112, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_011047:255208*25520828174126534Candidatus Phytoplasma mali, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_000963:20554620554622772522180Rickettsia prowazekii str. Madrid E, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_006833:637964*63796465659918636Wolbachia endosymbiont strain TRS of Brugia malayi, complete1e-1075.8BLASTN svgBLASTP svg
NC_020195:234392*23439225309918708Blattabacterium sp. (Blatta orientalis) str. Tarazona, complete6e-1073.8BLASTN svgBLASTP svg
NC_013517:82510082510084990924810Sebaldella termitidis ATCC 33386, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_005303:780557*78055780913328577Onion yellows phytoplasma OY-M, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_004061:146862*14686216626919408Buchnera aphidicola str. Sg (Schizaphis graminum), complete genome6e-1073.8BLASTN svgBLASTP svg
NC_002528:148274*14827417635828085Buchnera aphidicola str. APS (Acyrthosiphon pisum), complete2e-0971.9BLASTN svgBLASTP svg
NC_007633:446899*44689946595419056Mycoplasma capricolum subsp. capricolum ATCC 27343, complete2e-0971.9BLASTN svgBLASTP svg
NC_014751:449001*44900146805619056Mycoplasma leachii PG50 chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_020291:4357425*4357425438031722893Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-0971.9BLASTN svgBLASTP svg
NC_000908:160072*16007221039050319Mycoplasma genitalium G37, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_009850:2169459*2169459220320233744Arcobacter butzleri RM4018, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014499:87528*8752810905021523Candidatus Sulcia muelleri CARI chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_014004:66631*666318870622076Candidatus Sulcia muelleri DMIN chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_004545:141478*14147816560324126Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genome6e-0763.9BLASTN svgBLASTP svg
NC_010674:30495003049500307069321194Clostridium botulinum B str. Eklund 17B, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_013123:78786*7878610552026735Candidatus Sulcia muelleri SMDSEM, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015662:110950*11095013012219173Buchnera aphidicola (Cinara tujafilina) chromosome, complete6e-0763.9BLASTN svgBLASTP svg
NC_018507:339000*33900036299924000Candidatus Portiera aleyrodidarum BT-B chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_018677:329829*32982935599926171Candidatus Portiera aleyrodidarum BT-B-HRs chromosome, complete6e-0763.9BLASTN svgBLASTP svg
NC_015760:123929*12392914613122203Streptococcus salivarius CCHSS3, complete genome9e-0660BLASTN svgBLASTP svg
NC_009881:23650023650025585219353Rickettsia akari str. Hartford, complete genome9e-0660BLASTN svgBLASTP svg