Pre_GI: BLASTN Hits

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Query: NC_009565:3485772 Mycobacterium tuberculosis F11, complete genome

Start: 3485772, End: 3504774, Length: 19003

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (genotype F11) represents the largest portion of isolates recovered from tuberculosis patients during a TB epidemic in the Western Cape of South Africa. Causative agent of tuberculosis. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_002755:34655823465582349023924658Mycobacterium tuberculosis CDC1551, complete genome022350BLASTN svgBLASTP svg
NC_009525:34849243484924350559920676Mycobacterium tuberculosis H37Ra, complete genome022340BLASTN svgBLASTP svg
NC_000962:34740003474000349418120182Mycobacterium tuberculosis H37Rv, complete genome022340BLASTN svgBLASTP svg
NC_012207:34211443421144344072619583Mycobacterium bovis BCG str. Tokyo 172, complete genome012570BLASTN svgBLASTP svg
NC_008769:34272543427254344807620823Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome012570BLASTN svgBLASTP svg
NC_002945:34293153429315345013820824Mycobacterium bovis AF2122/97, complete genome012550BLASTN svgBLASTP svg
NC_000962:31168183116818313633319516Mycobacterium tuberculosis H37Rv, complete genome02688BLASTN svgBLASTP svg
NC_002755:31109293110929312975718829Mycobacterium tuberculosis CDC1551, complete genome02688BLASTN svgBLASTP svg
NC_002945:30733703073370309459921230Mycobacterium bovis AF2122/97, complete genome02688BLASTN svgBLASTP svg
NC_008769:30702663070266308959919334Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome02688BLASTN svgBLASTP svg
NC_009525:31287863128786314904720262Mycobacterium tuberculosis H37Ra, complete genome02688BLASTN svgBLASTP svg
NC_009565:31280943128094314823720144Mycobacterium tuberculosis F11, complete genome02688BLASTN svgBLASTP svg
NC_012207:30630393063039308477921741Mycobacterium bovis BCG str. Tokyo 172, complete genome02688BLASTN svgBLASTP svg
NC_009525:37940003794000381625122252Mycobacterium tuberculosis H37Ra, complete genome02686BLASTN svgBLASTP svg
NC_009525:2635792*2635792265864122850Mycobacterium tuberculosis H37Ra, complete genome02686BLASTN svgBLASTP svg
NC_000962:37815013781501380757326073Mycobacterium tuberculosis H37Rv, complete genome02686BLASTN svgBLASTP svg
NC_002755:47287247287249645723586Mycobacterium tuberculosis CDC1551, complete genome02680BLASTN svgBLASTP svg
NC_009077:2308634*2308634235649847865Mycobacterium sp. JLS, complete genome0775BLASTN svgBLASTP svg
NC_011896:78150078150080335521856Mycobacterium leprae Br4923, complete genome1e-128468BLASTN svgBLASTP svg
NC_014814:13240413240415486122458Mycobacterium sp. Spyr1 chromosome, complete genome8e-111408BLASTN svgBLASTP svg
NC_015848:2684275*2684275270528621012Mycobacterium canettii CIPT 140010059, complete genome3e-101377BLASTN svgBLASTP svg
NC_008726:49476949476951509920331Mycobacterium vanbaalenii PYR-1, complete genome5e-78299BLASTN svgBLASTP svg
NC_013235:2257899*2257899229859940701Nakamurella multipartita DSM 44233, complete genome8e-74285BLASTN svgBLASTP svg
NC_013235:40455894045589406814822560Nakamurella multipartita DSM 44233, complete genome3e-67264BLASTN svgBLASTP svg
NC_013235:13544431354443137485420412Nakamurella multipartita DSM 44233, complete genome2e-62248BLASTN svgBLASTP svg
NC_010612:4501414*4501414452499223579Mycobacterium marinum M, complete genome9e-46192BLASTN svgBLASTP svg
NC_008699:4443000*4443000447766734668Nocardioides sp. JS614, complete genome1e-38168BLASTN svgBLASTP svg
NC_008268:34180003418000344059922600Rhodococcus sp. RHA1, complete genome1e-35159BLASTN svgBLASTP svg
NC_014151:40213944021394406852347130Cellulomonas flavigena DSM 20109 chromosome, complete genome5e-35157BLASTN svgBLASTP svg
NC_015312:1191633*1191633121600524373Pseudonocardia dioxanivorans CB1190 chromosome, complete genome2e-34155BLASTN svgBLASTP svg
NC_014815:658893*65889368838329491Micromonospora sp. L5 chromosome, complete genome8e-34153BLASTN svgBLASTP svg
NC_014391:4672105*4672105470459932495Micromonospora aurantiaca ATCC 27029 chromosome, complete genome8e-34153BLASTN svgBLASTP svg
NC_014391:1812500*1812500186094748448Micromonospora aurantiaca ATCC 27029 chromosome, complete genome8e-34153BLASTN svgBLASTP svg
NC_008268:75763657576365760084724483Rhodococcus sp. RHA1, complete genome1e-32149BLASTN svgBLASTP svg
NC_008271:24837124837127209923729Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence1e-32149BLASTN svgBLASTP svg
NC_013131:997692999769291000446227534Catenulispora acidiphila DSM 44928, complete genome1e-29139BLASTN svgBLASTP svg
NC_008146:15358271535827156295027124Mycobacterium sp. MCS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008146:15776041577604160675629153Mycobacterium sp. MCS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008146:86131986131994414682828Mycobacterium sp. MCS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:1022252*1022252104828626035Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:15370801537080155764220563Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:15577111557711161059952889Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:27434*274345721729784Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:5144433*5144433517009925667Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_008705:86862386862395099082368Mycobacterium sp. KMS, complete genome2e-28135BLASTN svgBLASTP svg
NC_013729:863743*86374390229738555Kribbella flavida DSM 17836, complete genome2e-25125BLASTN svgBLASTP svg
NC_008705:17902221790222183895348732Mycobacterium sp. KMS, complete genome1e-23119BLASTN svgBLASTP svg
NC_008595:22528302252830227372020891Mycobacterium avium 104, complete genome2e-19105BLASTN svgBLASTP svg
NC_008595:22152442215244224973534492Mycobacterium avium 104, complete genome2e-19105BLASTN svgBLASTP svg
NC_009921:1645380*1645380166750622127Frankia sp. EAN1pec, complete genome3e-18101BLASTN svgBLASTP svg
NC_009921:3384116*3384116340895324838Frankia sp. EAN1pec, complete genome3e-18101BLASTN svgBLASTP svg
NC_009921:3551036*3551036362235971324Frankia sp. EAN1pec, complete genome3e-18101BLASTN svgBLASTP svg
NC_012803:17531381753138177628023143Micrococcus luteus NCTC 2665, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_013235:3812838*3812838384142328586Nakamurella multipartita DSM 44233, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_008435:1215437*1215437131209196655Rhodopseudomonas palustris BisA53, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_014815:841484*84148489809956616Micromonospora sp. L5 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_014814:2588628*2588628264757658949Mycobacterium sp. Spyr1 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_008752:29369332936933297832941397Acidovorax avenae subsp. citrulli AAC00-1, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008752:32176953217695323954921855Acidovorax avenae subsp. citrulli AAC00-1, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_010125:10517351051735108259930865Gluconacetobacter diazotrophicus PAl 5, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_013169:1845735*1845735186893023196Kytococcus sedentarius DSM 20547, complete genome9e-0660BLASTN svgBLASTP svg
NC_013169:513327*51332754059927273Kytococcus sedentarius DSM 20547, complete genome9e-0660BLASTN svgBLASTP svg
NC_014931:25114232511423253417122749Variovorax paradoxus EPS chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014931:29496972949697297109921403Variovorax paradoxus EPS chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014931:4210029*4210029424439734369Variovorax paradoxus EPS chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014931:4234288*4234288426496730680Variovorax paradoxus EPS chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_014931:55739425573942559409920158Variovorax paradoxus EPS chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_015434:666692*66669270459937908Verrucosispora maris AB-18-032 chromosome, complete genome9e-0660BLASTN svgBLASTP svg
NC_008314:1955793*1955793197880923017Ralstonia eutropha H16 chromosome 2, complete sequence9e-0660BLASTN svgBLASTP svg