Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:781500 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
793601793882282hypothetical proteinBLASTP
795546795872327hypothetical proteinBLASTP
7960567972581203putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
7973017986981398putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
798775799542768putative monophosphataseQuickGO ontologyBLASTP
799670799984315hypothetical proteinBLASTP
800125800388264hypothetical proteinBLASTP
8019858033551371putative NADPH-ferredoxin reductaseQuickGO ontologyBLASTP