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Query: NC_012658:2498087:2504740 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 2504740, End: 2505606, Length: 867

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009697:3110772:311362931136293114498870Clostridium botulinum A str. ATCC 19397 chromosome, completehypothetical protein7e-114410
NC_009697:2558286:256391725639172564783867Clostridium botulinum A str. ATCC 19397 chromosome, completephage tail protein7e-94343
NC_010516:2676746:268234926823492683215867Clostridium botulinum B1 str. Okra, complete genomeputative phage tail protein2e-92338
NC_017297:3428429:343414034341403435009870Clostridium botulinum F str. 230613 chromosome, complete genomeputative phage tail protein9e-92336
NC_009699:3429817:343552834355283436397870Clostridium botulinum F str. Langeland chromosome, complete genomephage tail protein9e-92336
NC_018515:4660808:467015946701594671022864Desulfosporosinus meridiei DSM 13257 chromosome, complete genomePhage tail protein1e-70266
NC_017297:2017000:202107820210782021947870Clostridium botulinum F str. 230613 chromosome, complete genomehypothetical protein3e-63241
NC_009699:2017329:202097320209732021842870Clostridium botulinum F str. Langeland chromosome, complete genomehypothetical protein3e-63241
NC_012563:2101449:210915321091532110022870Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein4e-63241
NC_012563:2925472:293350729335072934376870Clostridium botulinum A2 str. Kyoto, complete genomehypothetical protein1e-62239
NC_009706:2673906:270705327070532707904852Clostridium kluyveri DSM 555 chromosome, complete genomehypothetical protein2e-53209
NC_011837:2605409:263855626385562639407852Clostridium kluyveri NBRC 12016, complete genomehypothetical protein2e-53209
NC_016791:4038069:405227240522724053123852Clostridium sp. BNL1100 chromosome, complete genomephage tail protein2e-51202
NC_016048:3899878:392113039211303921981852Oscillibacter valericigenes Sjm18-20, complete genomehypothetical protein1e-49197
NC_013411:597235:627980627980628843864Geobacillus sp. Y412MC61, complete genomephage-related putative tail protein2e-47189
NC_014915:2963500:297509229750922975955864Geobacillus sp. Y412MC52 chromosome, complete genomephage-related putative tail protein2e-47189
NC_010516:2305110:231572623157262316589864Clostridium botulinum B1 str. Okra, complete genomephage related protein2e-46186
NC_015690:1186545:122622812262281227079852Paenibacillus mucilaginosus KNP414 chromosome, complete genomephage-like protein (tail protein)2e-37156
NC_016935:1636278:167567816756781676529852Paenibacillus mucilaginosus 3016 chromosome, complete genomephage-like protein4e-36152
NC_014393:2868846:287834128783412879201861Clostridium cellulovorans 743B chromosome, complete genometail component family protein5e-35148
NC_021184:4493440:450927245092724510123852Desulfotomaculum gibsoniae DSM 7213, complete genomehypothetical protein1e-34147
NC_015519:2489728:250919025091902510041852Tepidanaerobacter sp. Re1 chromosome, complete genomephage-related putative tail protein3e-32139