Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:2305110 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
23051102306000891transcriptional regulator AraC familyQuickGO ontologyBLASTP
23063012306822522hypothetical proteinBLASTP
23093842309605222hypothetical protein
23100152310788774N-acetylmuramoyl-L-alanine amidaseQuickGO ontologyBLASTP
23108322311026195hypothetical proteinBLASTP
23110432311297255hypothetical proteinBLASTP
23114642311931468hypothetical protein
23120682312190123hypothetical proteinBLASTP
23121832312548366hypothetical proteinBLASTP
231256123143661806putative tail fiber proteinQuickGO ontologyBLASTP
231437323155301158hypothetical proteinBLASTP
23157262316589864phage related proteinQuickGO ontologyBLASTP
231657923191942616phage proteinQuickGO ontologyBLASTP
23192452319406162hypothetical proteinBLASTP
23194392319933495hypothetical proteinBLASTP
23199802320573594putative protein gp15QuickGO ontologyBLASTP
23205732320917345hypothetical proteinBLASTP
23209812321187207hypothetical protein
23212042321428225hypothetical protein
23214322321926495hypothetical proteinBLASTP
23219272322361435hypothetical proteinBLASTP
23223582322702345hypothetical proteinBLASTP
23227022323112411hypothetical proteinBLASTP
23231142323380267hypothetical proteinBLASTP
23233702323555186hypothetical protein
23236052324552948prophage LambdaCh01 coat proteinQuickGO ontologyBLASTP
23245762325214639hypothetical proteinBLASTP
23254832326076594hypothetical proteinBLASTP
23262852327007723hypothetical proteinBLASTP
232700723282841278phage portal protein SPP1 familyQuickGO ontologyBLASTP