Pre_GI: BLASTN Hits

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Query: NC_017026:1686500 Mycobacterium tuberculosis RGTB327 chromosome, complete genome

Start: 1686500, End: 1710672, Length: 24173

Host Lineage: Mycobacterium tuberculosis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of tuberculosis - a chronic infectious disease with a growing incidence worldwide. It infects 1.7 billion people a year (~33% of the entire world population) and causes over 3 million deaths/year. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. This bacterium does not form a polysaccharide capsule, and is an extremely slow growing obligate aerobe. The sluggish growth rate is a result of the tough cell wall that resists the passage of nutrients into the cell and inhibits waste products to be excreted out of the cell. The specialized cell envelope of this organism resembles a modified Gram positive cell wall. It also contains complex fatty acids, such as mycolic acids, that cause the waxy appearance and impermeability of the envelope. These acids are found bound to the cell envelope, but also form cord factors when linked with a carbohydrate component to form a cord-like structure. Primary infection occurs by inhalation of the organism in droplets that are aerosolized by an infected person. The organism initially replicates in cells of the terminal airways, after which it is taken up by, and replicates in, alveolar macrophages. Macrophages distribute the organism to other areas of the lungs and the regional lymph nodes. Once a cell-mediated hypersensitivity immune response develops, replication of the organism decreases and the bacteria become restricted to developing granulomas.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009525:16855221685522171115225631Mycobacterium tuberculosis H37Ra, complete genome047320BLASTN svgBLASTP svg
NC_002755:16841611684161170880524645Mycobacterium tuberculosis CDC1551, complete genome045360BLASTN svgBLASTP svg
NC_000962:16840051684005170853924535Mycobacterium tuberculosis H37Rv, complete genome045160BLASTN svgBLASTP svg
NC_015848:17081761708176173271724542Mycobacterium canettii CIPT 140010059, complete genome044750BLASTN svgBLASTP svg
NC_009565:16886421688642171216323522Mycobacterium tuberculosis F11, complete genome043190BLASTN svgBLASTP svg
NC_019950:16899101689910171687926970Mycobacterium canettii CIPT 140060008 complete genome030510BLASTN svgBLASTP svg
NC_012207:16819711681971170520423234Mycobacterium bovis BCG str. Tokyo 172, complete genome020600BLASTN svgBLASTP svg
NC_008769:17090781709078173231123234Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome020600BLASTN svgBLASTP svg
NC_002945:16807511680751170398323233Mycobacterium bovis AF2122/97, complete genome020600BLASTN svgBLASTP svg
NC_010612:27776872777687279716619480Mycobacterium marinum M, complete genome0763BLASTN svgBLASTP svg
NC_002944:12854361285436132132435889Mycobacterium avium subsp. paratuberculosis K-10, complete genome0670BLASTN svgBLASTP svg
NC_008268:5781604*5781604581424432641Rhodococcus sp. RHA1, complete genome4e-79303BLASTN svgBLASTP svg
NC_018581:11809511180951122156540615Gordonia sp. KTR9 chromosome, complete genome2e-59238BLASTN svgBLASTP svg
NC_009525:2635792*2635792265864122850Mycobacterium tuberculosis H37Ra, complete genome8e-53216BLASTN svgBLASTP svg
NC_015848:2684275*2684275270528621012Mycobacterium canettii CIPT 140010059, complete genome1e-51212BLASTN svgBLASTP svg
NC_014100:533322*53332256190028579Caulobacter segnis ATCC 21756 chromosome, complete genome1e-23119BLASTN svgBLASTP svg
NC_015125:24439452443945246359819654Microbacterium testaceum StLB037, complete genome5e-20107BLASTN svgBLASTP svg
NC_011145:49609404960940498025219313Anaeromyxobacter sp. K, complete genome2e-19105BLASTN svgBLASTP svg
NC_000962:32884643288464331029721834Mycobacterium tuberculosis H37Rv, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_002755:32827853282785330371920935Mycobacterium tuberculosis CDC1551, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_002945:32462783246278326609919822Mycobacterium bovis AF2122/97, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_008769:32424533242453326356021108Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_009525:33004563300456332228921834Mycobacterium tuberculosis H37Ra, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_009565:32999373299937332177021834Mycobacterium tuberculosis F11, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_012207:32374403237440325728519846Mycobacterium bovis BCG str. Tokyo 172, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_015848:33437313343731336691823188Mycobacterium canettii CIPT 140010059, complete genome1e-1799.6BLASTN svgBLASTP svg
NC_019950:33064193306419333122724809Mycobacterium canettii CIPT 140060008 complete genome1e-1799.6BLASTN svgBLASTP svg
NC_007760:49111814911181493806026880Anaeromyxobacter dehalogenans 2CP-C, complete genome5e-1797.6BLASTN svgBLASTP svg
NC_014034:995661*995661102273727077Rhodobacter capsulatus SB1003 chromosome, complete genome3e-1591.7BLASTN svgBLASTP svg
NC_009937:1733196*1733196175210518910Azorhizobium caulinodans ORS 571, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_008146:1016446*1016446104459328148Mycobacterium sp. MCS, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_008702:39280433928043395047222430Azoarcus sp. BH72, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_004463:17725411772541179709924559Bradyrhizobium japonicum USDA 110, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_008702:2942246*2942246296909926854Azoarcus sp. BH72, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_013446:26559552655955268195826004Comamonas testosteroni CNB-2, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014973:28942482894248291621621969Geobacter sp. M18 chromosome, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_007517:1468719*1468719150798939271Geobacter metallireducens GS-15, complete genome3e-0661.9BLASTN svgBLASTP svg