Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:1680751 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
168075116830032253methylmalonyl-CoA mutaseQuickGO ontologyBLASTP
16830171683319303hypothetical proteinBLASTP
16833161683633318hypothetical proteinBLASTP
168363016846341005arginineornithine transport system ATPaseQuickGO ontologyBLASTP
168468716859761290esterase LipLQuickGO ontologyBLASTP
16860491686666618methyltransferaseQuickGO ontologyBLASTP
16868801687071192hypothetical proteinBLASTP
16871531687551399hypothetical proteinBLASTP
168759616886241029glycosyltransferaseQuickGO ontologyBLASTP
16886361689457822hypothetical proteinBLASTP
16896701690020351hypothetical proteinBLASTP
16899991690568570hypothetical proteinBLASTP
169074116918891149TDP-4-oxo-6-deoxy-D-glucose transaminaseQuickGO ontologyBLASTP
16920261692691666hypothetical proteinBLASTP
16928841693648765hypothetical proteinBLASTP
16936571694616960hypothetical proteinBLASTP
16947461695015270hypothetical proteinBLASTP
169504116960811041sugar transferaseQuickGO ontologyBLASTP
169631516980661752acyl-CoA synthetaseQuickGO ontologyBLASTP
169830217016253324transmembrane transport protein MmpL12QuickGO ontologyBLASTP
170166617027091044methyltransferaseQuickGO ontologyBLASTP
170273917039831245glycosyltransferaseQuickGO ontologyBLASTP