Pre_GI Gene

Some Help

Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:7706226 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
770622677077431518sensor histidine-kinaseQuickGO ontologyBLASTP
770777177096721902hypothetical proteinBLASTP
77098767710085210hypothetical protein
77101677710406240hypothetical protein
771044677119511506hypothetical proteinBLASTP
77119707712521552hypothetical proteinBLASTP
77128057713266462hypothetical proteinBLASTP
771342577148281404hypothetical proteinBLASTP
77148257715706882hypothetical proteinBLASTP
771580177168441044hypothetical proteinBLASTP
771786477194411578hypothetical proteinBLASTP
771981777227202904probable NADH dehydrogenase I complex subunitQuickGO ontologyBLASTP
77227177723481765hypothetical protein
772347877252171740oxidoreductaseQuickGO ontologyBLASTP
77252147725813600hypothetical proteinBLASTP
77258107726127318membrane proteinQuickGO ontology
77261247726489366membrane proteinQuickGO ontologyBLASTP
77265037727039537hypothetical proteinBLASTP
772711177282591149hypothetical proteinBLASTP