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Query: NC_003888:7706226:7714825 Streptomyces coelicolor A3(2), complete genome

Start: 7714825, End: 7715706, Length: 882

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007777:2749422:275368627536862754600915Frankia sp. CcI3, complete genomehypothetical protein6e-68257
NC_018750:6192970:620358862035886204481894Streptomyces venezuelae ATCC 10712, complete genomehypothetical protein9e-68256
NC_016887:2269177:228673422867342287627894Nocardia cyriacigeorgica GUH-2, complete genomehypothetical protein6e-67254
NC_016109:3963189:398568939856893986465777Kitasatospora setae KM-6054, complete genomehypothetical protein3e-44178
NC_013093:1213908:122844212284421229353912Actinosynnema mirum DSM 43827, complete genomeaminoglycoside phosphotransferase1e-41170
NC_013929:5927935:594396259439625944876915Streptomyces scabiei 87.22 chromosome, complete genomedetoxifying phosphotransferase4e-39162
NC_016111:3486000:348867934886793489605927Streptomyces cattleya NRRL 8057, complete genomeaminoglycoside phosphotransferase3e-39162
NC_018524:557666:582508582508583404897Nocardiopsis alba ATCC BAA-2165 chromosome, complete genomephosphotransferase enzyme family protein3e-37155
NC_014210:4122514:413346541334654134235771Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,aminoglycoside phosphotransferase4e-36151
NC_019673:8799533:881574488157448816685942Saccharothrix espanaensis DSM 44229 complete genomeAminoglycoside phosphotransferase1e-35150
NC_014318:9604367:961973596197359620631897Amycolatopsis mediterranei U32 chromosome, complete genomehypothetical protein3e-34145
NC_017186:9604427:961979596197959620691897Amycolatopsis mediterranei S699 chromosome, complete genomehypothetical protein3e-34145
NC_009953:1364500:137365313736531374561909Salinispora arenicola CNS-205 chromosome, complete genomeaminoglycoside phosphotransferase3e-34145
NC_017186:6817904:682725268272526827875624Amycolatopsis mediterranei S699 chromosome, complete genomeaminoglycoside phosphotransferase1e-28127
NC_013510:3117837:314242631424263143331906Thermomonospora curvata DSM 43183, complete genomeaminoglycoside phosphotransferase2e-22106
NC_013929:2375613:245931124593112460084774Streptomyces scabiei 87.22 chromosome, complete genomephosphotransferase3e-22105
NC_009142:267550:283817283817284437621Saccharopolyspora erythraea NRRL 2338, complete genomeaminoglycoside phosphotransferase6e-22104
NC_015434:2438202:244374424437442444628885Verrucosispora maris AB-18-032 chromosome, complete genomeaminoglycoside phosphotransferase8e-22104
NC_015434:1173794:118630311863031187193891Verrucosispora maris AB-18-032 chromosome, complete genomeaminoglycoside phosphotransferase6e-1788.2
NC_014666:1844882:185899918589991859880882Frankia sp. EuI1c chromosome, complete genomeaminoglycoside phosphotransferase1e-1584