Pre_GI: BLASTP Hits

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Query: NC_003888:7706226:7715801 Streptomyces coelicolor A3(2), complete genome

Start: 7715801, End: 7716844, Length: 1044

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_005140:340000:3513233513233523391017Vibrio vulnificus YJ016 chromosome II, complete sequencehypothetical protein2e-39163
NC_007712:1516589:1528945152894515300601116Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein1e-32140
NC_015968:3301958:3313377331337733144861110Enterobacter asburiae LF7a chromosome, complete genomeRelA/SpoT domain-containing protein3e-31136
NC_008380:2210649:2223311222331122244711161Rhizobium leguminosarum bv. viciae 3841, complete genomehypothetical protein3e-30132
NC_020260:440000:4474354474354485351101Cronobacter sakazakii Sp291, complete genomeGTP pyrophosphokinase1e-28127
NC_012918:1660477:1671703167170316728481146Geobacter sp. M21 chromosome, complete genomeRelA/SpoT domain-containing protein2e-27123
NC_013209:867500:8747428747428758601119Acetobacter pasteurianus IFO 3283-01, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017100:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-03, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017108:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-12, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017111:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-32, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017121:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-07, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017125:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-22, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017146:867500:8747368747368758541119Acetobacter pasteurianus IFO 3283-26, complete genomestringent response modulating ppGpp metabolism protein3e-26119
NC_017045:1:426442645052789Riemerella anatipestifer ATCC 11845 = DSM 15868 chromosome,putative BCR/ Guanosine polyphosphate pyrophosphohydrolase/ synthetase7e-23108
NC_014121:2090630:209746720974672098267801Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, completehypothetical protein2e-1893.6