Pre_GI: BLASTP Hits

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Query: NC_004088:266543:276826 Yersinia pestis KIM, complete genome

Start: 276826, End: 276924, Length: 99

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_014029:3958811:3978308397830839805062199Yersinia pestis Z176003 chromosome, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_017168:1631052:1650549165054916527472199Yersinia pestis A1122 chromosome, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_017154:3898925:3909423390942339118252403Yersinia pestis D106004 chromosome, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_006155:4302826:4302826430282643050242199Yersinia pseudotuberculosis IP 32953, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_017154:3898925:3918422391842239206202199Yersinia pestis D106004 chromosome, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_017160:4073611:4090590409059040929922403Yersinia pestis D182038 chromosome, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_005810:4469156:4486328448632844887302403Yersinia pestis biovar Microtus str. 91001, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_017160:4073611:4081795408179540839932199Yersinia pestis D182038 chromosome, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_005810:4469156:4477533447753344797312199Yersinia pestis biovar Microtus str. 91001, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_017265:4265659:4265659426565942678572199Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative Rhs accessory genetic element2e-1064.3
NC_017168:1631052:1641550164155016439522403Yersinia pestis A1122 chromosome, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_003143:4006884:4017382401738240197842403Yersinia pestis CO92, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_003143:4006884:4026381402638140285792199Yersinia pestis CO92, complete genomeputative Rhs accessory genetic element2e-1064.3
NC_017265:4265659:4274456427445642768582403Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative Rhs accessory genetic element9e-1062.4
NC_014029:3958811:3969309396930939717112403Yersinia pestis Z176003 chromosome, complete genomeputative Rhs accessory genetic element9e-1062.4
NC_006155:4302826:4311861431186143140802220Yersinia pseudotuberculosis IP 32953, complete genomeputative Rhs accessory genetic element9e-0855.5
NC_008149:4053363:4070342407034240727442403Yersinia pestis Nepal516, complete genomeRhs accessory genetic element9e-1062.4
NC_008149:4053363:4061547406154740637452199Yersinia pestis Nepal516, complete genomeRhs accessory genetic element2e-1064.3
NC_009381:222735:2332242332242356142391Yersinia pestis Pestoides F chromosome, complete genomeRhs accessory genetic element9e-1062.4
NC_009381:222735:2422112422112444092199Yersinia pestis Pestoides F chromosome, complete genomeRhs accessory genetic element2e-1064.3
NC_009708:372422:3829483829483851702223Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeRhs element Vgr protein8e-1062.4
NC_010465:429095:4395884395884418102223Yersinia pseudotuberculosis YPIII, complete genometype VI secretion system Vgr family protein8e-1062.4
NC_010634:4234932:4242979424297942451772199Yersinia pseudotuberculosis PB1/+, complete genometype VI secretion system Vgr family protein9e-1062.4
NC_004088:266543:2835212835212859232403Yersinia pestis KIM, complete genomeVgrG-like protein9e-1062.4