Query: NC_011896:1462258 Mycobacterium leprae Br4923, complete genome
Start: 1462258, End: 1488376, Length: 26119
Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_002677:1462233 | 1462233 | 1488352 | 26120 | Mycobacterium leprae TN, complete genome | 0 | 51650 | BLASTN svg | BLASTP svg |
NC_012207:2747599 | 2747599 | 2771480 | 23882 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 6e-57 | 230 | BLASTN svg | BLASTP svg |
NC_009525:2802987 | 2802987 | 2826879 | 23893 | Mycobacterium tuberculosis H37Ra, complete genome | 6e-57 | 230 | BLASTN svg | BLASTP svg |
NC_008769:2754828 | 2754828 | 2778707 | 23880 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 6e-57 | 230 | BLASTN svg | BLASTP svg |
NC_002945:2757821 | 2757821 | 2781708 | 23888 | Mycobacterium bovis AF2122/97, complete genome | 6e-57 | 230 | BLASTN svg | BLASTP svg |
NC_000962:2791019 | 2791019 | 2814911 | 23893 | Mycobacterium tuberculosis H37Rv, complete genome | 6e-57 | 230 | BLASTN svg | BLASTP svg |
NC_009565:2806000 | 2806000 | 2828229 | 22230 | Mycobacterium tuberculosis F11, complete genome | 2e-38 | 168 | BLASTN svg | BLASTP svg |
NC_002755:2788000 | 2788000 | 2810399 | 22400 | Mycobacterium tuberculosis CDC1551, complete genome | 2e-38 | 168 | BLASTN svg | BLASTP svg |
NC_010730:952574* | 952574 | 971192 | 18619 | Sulfurihydrogenibium sp. YO3AOP1, complete genome | 3e-15 | 91.7 | BLASTN svg | BLASTP svg |
NC_014550:2091797* | 2091797 | 2129976 | 38180 | Arthrobacter arilaitensis Re117, complete genome | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_012440:1841315* | 1841315 | 1867604 | 26290 | Persephonella marina EX-H1, complete genome | 2e-10 | 75.8 | BLASTN svg | BLASTP svg |
NC_013851:2317091* | 2317091 | 2338933 | 21843 | Allochromatium vinosum DSM 180 chromosome, complete genome | 8e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_013093:1213908* | 1213908 | 1243375 | 29468 | Actinosynnema mirum DSM 43827, complete genome | 8e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_011896:173197 | 173197 | 191988 | 18792 | Mycobacterium leprae Br4923, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_006087:1334500* | 1334500 | 1362292 | 27793 | Leifsonia xyli subsp. xyli str. CTCB07, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_002677:173170 | 173170 | 191961 | 18792 | Mycobacterium leprae TN, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_011138:3182807* | 3182807 | 3211655 | 28849 | Alteromonas macleodii 'Deep ecotype', complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014216:2538500* | 2538500 | 2563870 | 25371 | Desulfurivibrio alkaliphilus AHT2 chromosome, complete genome | 5e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_002944:4163490 | 4163490 | 4199728 | 36239 | Mycobacterium avium subsp. paratuberculosis K-10, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_020411:114683* | 114683 | 151518 | 36836 | Hydrogenobaculum sp. HO, complete genome | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015587:114684* | 114684 | 151519 | 36836 | Hydrogenobaculum sp. SHO chromosome, complete genome | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_015557:114648* | 114648 | 151483 | 36836 | Hydrogenobaculum sp. 3684 chromosome, complete genome | 8e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_009565:1866214 | 1866214 | 1890742 | 24529 | Mycobacterium tuberculosis F11, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_009525:1872360 | 1872360 | 1896860 | 24501 | Mycobacterium tuberculosis H37Ra, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_008769:1876109 | 1876109 | 1900616 | 24508 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_002945:1856228 | 1856228 | 1880738 | 24511 | Mycobacterium bovis AF2122/97, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_012207:1848091 | 1848091 | 1869245 | 21155 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_013282:1200993 | 1200993 | 1249279 | 48287 | Cronobacter turicensis, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_015848:1896660 | 1896660 | 1922091 | 25432 | Mycobacterium canettii CIPT 140010059, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_019950:1870863 | 1870863 | 1896294 | 25432 | Mycobacterium canettii CIPT 140060008 complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_020064:1150982* | 1150982 | 1170406 | 19425 | Serratia marcescens FGI94, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_020260:2725201* | 2725201 | 2758823 | 33623 | Cronobacter sakazakii Sp291, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_000962:1870842 | 1870842 | 1895342 | 24501 | Mycobacterium tuberculosis H37Rv, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |