Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:2757821 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
275608227578241743bifunctionnal putative L-3-phosphoserine phosphatase1-acyl-SN-glycerol-3-phosphate acyltransferaseQuickGO ontologyBLASTP
275782127592961476hypothetical proteinBLASTP
275952527607901266carboxylesterase LipQQuickGO ontologyBLASTP
27611522761922771enoyl-CoA hydrataseQuickGO ontologyBLASTP
27635662764186621hypothetical proteinBLASTP
276426827676813414LuxR family transcriptional regulatorQuickGO ontologyBLASTP
27676472767946300hypothetical proteinBLASTP
276805527715073453hypothetical protein
277150427730331530hypothetical proteinBLASTP
27734622774085624hypothetical proteinBLASTP
27740752774827753hypothetical proteinBLASTP
27748802775101222hypothetical proteinBLASTP
27751072775532426hypothetical proteinBLASTP
277555527767361182branched-chain alpha-keto acid dehydrogenase subunit E2QuickGO ontologyBLASTP
277673327777791047pyruvate dehydrogenase E1 component beta subunit PdhBQuickGO ontologyBLASTP
277779027788931104pyruvate dehydrogenase E1 component alpha subunit PdhAQuickGO ontologyBLASTP
27791522779973822citrate Pro-3S-lyase beta subunitQuickGO ontologyBLASTP
27799702780527558oxidase regulatory-like proteinQuickGO ontologyBLASTP
278052427817081185acyl-CoA dehydrogenaseQuickGO ontologyBLASTP