Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:2747599 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
274586027476021743putative transmembrane phospholipid biosynthesis enzymeQuickGO ontologyBLASTP
274759927490741476hypothetical proteinBLASTP
274930327505681266putative carboxylesteraseQuickGO ontologyBLASTP
27509302751700771enoyl-CoA hydrataseQuickGO ontologyBLASTP
275238027539631584PE-PGRS family proteinQuickGO ontologyBLASTP
275404527574583414putative transcriptional regulatory proteinQuickGO ontologyBLASTP
27574242757723300hypothetical alanine rich proteinQuickGO ontologyBLASTP
275796027612863327PE-PGRS family proteinQuickGO ontology
276137827628051428PE-PGRS family proteinQuickGO ontologyBLASTP
27632342763857624hypothetical proteinBLASTP
27638472764599753hypothetical proteinBLASTP
27646522764873222hypothetical proteinBLASTP
27648792765304426hypothetical proteinBLASTP
276532727665081182branched-chain alpha-keto acid dehydrogenase subunit E2QuickGO ontologyBLASTP
276650527675511047putative pyruvate dehydrogenase E1 component subunit betaQuickGO ontologyBLASTP
276756227686651104putative pyruvate dehydrogenase E1 component subunit alphaQuickGO ontologyBLASTP
27689242769745822putative citrate pro-3s-lyase subunit betaQuickGO ontologyBLASTP
27697422770299558putative oxidase regulatory-related proteinQuickGO ontologyBLASTP
277029627714801185putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP