Pre_GI: BLASTN Hits

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Query: NC_010674:658596 Clostridium botulinum B str. Eklund 17B, complete genome

Start: 658596, End: 677121, Length: 18526

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum B str. Eklund 17B is a nonproteolytic botulism neurotoxin B strain. This strain was isolated from marine sediments taken off the coast of Washington, USA and was not associated with botulism. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010723:62292862292864247719550Clostridium botulinum E3 str. Alaska E43, complete genome07014BLASTN svgBLASTP svg
NC_010674:31412283141228316494623719Clostridium botulinum B str. Eklund 17B, complete genome01651BLASTN svgBLASTP svg
NC_008593:21367592136759215512718369Clostridium novyi NT, complete genome0654BLASTN svgBLASTP svg
NC_008593:2020473*2020473204359923127Clostridium novyi NT, complete genome2e-117430BLASTN svgBLASTP svg
NC_010520:35800003580000360470824709Clostridium botulinum A3 str. Loch Maree, complete genome4e-60240BLASTN svgBLASTP svg
NC_012563:37298173729817376659036774Clostridium botulinum A2 str. Kyoto, complete genome7e-59236BLASTN svgBLASTP svg
NC_004557:25524182552418257431921902Clostridium tetani E88, complete genome8e-37163BLASTN svgBLASTP svg
NC_014328:77309577309579175318659Clostridium ljungdahlii ATCC 49587 chromosome, complete genome1e-35159BLASTN svgBLASTP svg
NC_020291:24875752487575251068823114Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome4e-20107BLASTN svgBLASTP svg
NC_021182:14735351473535149659923065Clostridium pasteurianum BC1, complete genome4e-20107BLASTN svgBLASTP svg
NC_014393:30556103055610307809922490Clostridium cellulovorans 743B chromosome, complete genome2e-19105BLASTN svgBLASTP svg
NC_014614:47857847857849868920112Clostridium sticklandii, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_014654:22170722170724588524179Halanaerobium sp. 'sapolanicus' chromosome, complete genome6e-1693.7BLASTN svgBLASTP svg
NC_003030:1037885*1037885106609928215Clostridium acetobutylicum ATCC 824, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_008599:29000*290005467125672Campylobacter fetus subsp. fetus 82-40, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_013171:636293*63629365943323141Anaerococcus prevotii DSM 20548, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_015680:1315040*1315040135525840219Pyrococcus yayanosii CH1 chromosome, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_015687:1037706*1037706106791230207Clostridium acetobutylicum DSM 1731 chromosome, complete genome2e-1281.8BLASTN svgBLASTP svg
NC_020291:59810065981006600872727722Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome2e-1281.8BLASTN svgBLASTP svg
NC_015634:2445396*2445396246386918474Bacillus coagulans 2-6 chromosome, complete genome9e-1279.8BLASTN svgBLASTP svg
NC_020291:74432974432976571421386Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome4e-1177.8BLASTN svgBLASTP svg
NC_018664:28776928776930695419186Clostridium acidurici 9a chromosome, complete genome4e-1177.8BLASTN svgBLASTP svg
NC_014393:36509573650957366964218686Clostridium cellulovorans 743B chromosome, complete genome1e-1075.8BLASTN svgBLASTP svg
NC_010184:66122666122668503723812Bacillus weihenstephanensis KBAB4, complete genome6e-1073.8BLASTN svgBLASTP svg
NC_016023:2163000*2163000219738434385Bacillus coagulans 36D1 chromosome, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_008593:15131071513107153682423718Clostridium novyi NT, complete genome2e-0971.9BLASTN svgBLASTP svg
NC_011296:10862231086223110477418552Thermodesulfovibrio yellowstonii DSM 11347, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_014219:999648999648102449324846Bacillus selenitireducens MLS10 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_015687:2632557*2632557266659934043Clostridium acetobutylicum DSM 1731 chromosome, complete genome9e-0969.9BLASTN svgBLASTP svg
NC_020291:63100006310000633341723418Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome9e-0969.9BLASTN svgBLASTP svg
NC_004722:65095065095066943618487Bacillus cereus ATCC 14579, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_008593:1797000*1797000182201325014Clostridium novyi NT, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_011565:665515*66551568883023316Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,4e-0867.9BLASTN svgBLASTP svg
NC_011772:64777864777866815320376Bacillus cereus G9842, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015474:983468*983468100758524118Pyrococcus sp. NA2 chromosome, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_014614:6115*61154920643092Clostridium sticklandii, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_015687:27964127964130219622556Clostridium acetobutylicum DSM 1731 chromosome, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_009850:628024*62802464679818775Arcobacter butzleri RM4018, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_008255:32855613285561330752421964Cytophaga hutchinsonii ATCC 33406, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_003030:27964327964330219822556Clostridium acetobutylicum ATCC 824, complete genome1e-0765.9BLASTN svgBLASTP svg
NC_005957:66795466795469053422581Bacillus thuringiensis serovar konkukian str. 97-27, complete6e-0763.9BLASTN svgBLASTP svg
NC_011296:102650*10265012914226493Thermodesulfovibrio yellowstonii DSM 11347, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_015474:723553*72355378401560463Pyrococcus sp. NA2 chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_018664:12799501279950129986019911Clostridium acidurici 9a chromosome, complete genome6e-0763.9BLASTN svgBLASTP svg
NC_020291:62740306274030629482420795Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome6e-0763.9BLASTN svgBLASTP svg
NC_014166:1077121*1077121110271725597Arcobacter nitrofigilis DSM 7299 chromosome, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_012108:23053272305327234281637490Desulfobacterium autotrophicum HRM2, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_008599:1291300*1291300131526123962Campylobacter fetus subsp. fetus 82-40, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_020291:22914182291418231430022883Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome9e-0660BLASTN svgBLASTP svg
NC_014964:55791055791057776519856Thermoanaerobacter brockii subsp. finnii Ako-1 chromosome, complete9e-0660BLASTN svgBLASTP svg
NC_009850:41309341309343688323791Arcobacter butzleri RM4018, complete genome9e-0660BLASTN svgBLASTP svg
NC_009718:1183816*1183816120664022825Fervidobacterium nodosum Rt17-B1, complete genome9e-0660BLASTN svgBLASTP svg