Pre_GI: BLASTP Hits

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Query: NC_017154:3898925:3902319 Yersinia pestis D106004 chromosome, complete genome

Start: 3902319, End: 3903005, Length: 687

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:4265659:428327642832764283962687Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,hypothetical protein8e-132469
NC_003143:4006884:401027840102784010964687Yersinia pestis CO92, complete genomehypothetical protein8e-132469
NC_009381:222735:226120226120226806687Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein8e-132469
NC_009708:372422:375816375816376502687Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein8e-132469
NC_014029:3958811:396220539622053962891687Yersinia pestis Z176003 chromosome, complete genomehypothetical protein8e-132469
NC_017168:1631052:163444616344461635132687Yersinia pestis A1122 chromosome, complete genomehypothetical protein8e-132469
NC_010465:429095:432489432489433175687Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein5e-131466
NC_006155:4302826:432049943204994321185687Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein4e-130463
NC_010634:4234932:425159642515964252282687Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein4e-130463
NC_012962:293976:307169307169307816648Photorhabdus asymbiotica, complete genomehypothetical protein6e-57220
NC_005126:349658:387412387412388059648Photorhabdus luminescens subsp. laumondii TTO1, complete genomehypothetical protein8e-56216
NC_014228:4331327:434334743433474344018672Xenorhabdus nematophila ATCC 19061, complete genomeconserved hypothetical protein (probable component of SST VI cluster)4e-53207
NC_013892:274297:282828282828283493666Xenorhabdus bovienii SS-2004 chromosome, complete genomehypothetical protein1e-51202
NC_011274:1094379:112128611212861122023738Salmonella enterica subsp. enterica serovar Gallinarum str. 287/91hypothetical protein5e-49194
NC_011205:1186097:121299412129941213731738Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853type VI secretion-associated protein5e-49194
CP002185:234719:247228247228247971744Escherichia coli W, complete genomeT6SS-associated protein6e-48190
CP002516:3863932:386393238639323864675744Escherichia coli KO11, complete genometype VI secretion-associated protein, VC_A0118 family6e-48190
NC_016822:246715:259248259248259991744Shigella sonnei 53G, complete genometype VI secretion-associated protein6e-48190
NC_016902:3863932:386393238639323864675744Escherichia coli KO11FL chromosome, complete genometype VI secretion-associated protein6e-48190
NC_015968:4117835:4141012414101241431262115Enterobacter asburiae LF7a chromosome, complete genomeSigma 54 interacting domain-containing protein5e-29127
NC_012913:1832500:184679518467951847421627Aggregatibacter aphrophilus NJ8700, complete genomehypothetical protein5e-0651.2