Pre_GI Gene

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Host: NC_011205 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011205:1186097 Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a bovine-adapted serovar that is genetically related to S. Enteritidis that lives in the bovine intestinal tract and can causes disease in humans. While rare in incidence, S. dublin infection classically produces a syndrome of sustained bacteremia with fever, resulting in high morbidity and mortality. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
118609711900593963trifunctional transcriptional regulatorproline dehydrogenasepyrroline-5-carboxylate dehydrogenaseQuickGO ontologyBLASTP
11901201190251132hypothetical proteinBLASTP
119048011919881509sodiumproline symporterQuickGO ontologyBLASTP
11937751194656882RpiR family transcriptional regulatorQuickGO ontologyBLASTP
119494211964381497sodium-glucosegalactose cotransporterQuickGO ontologyBLASTP
11967751197455681N-acetylmannosamine-6-phosphate 2-epimeraseQuickGO ontologyBLASTP
119796111991151155N-acetylneuraminic acid mutarotaseQuickGO ontologyBLASTP
11991601199852693oligogalacturonate-specific porinQuickGO ontologyBLASTP
120143012025331104oxidoreductase YjhCQuickGO ontologyBLASTP
12027001202978279GTP cyclohydrolase IIQuickGO ontologyBLASTP
12030721203242171hypothetical proteinBLASTP
12032811203406126hypothetical proteinBLASTP
12042941204428135hypothetical protein
12044251204796372hypothetical proteinBLASTP
12052651206137873peptidoglycan-binding LysMQuickGO ontologyBLASTP
12061701206649480HNH endonuclease domain-containing proteinQuickGO ontologyBLASTP
120666512080291365ImpA domain-containing proteinQuickGO ontologyBLASTP
120804012115013462hypothetical proteinBLASTP
121158012129921413ImpA domain-containing proteinQuickGO ontologyBLASTP
12129941213731738type VI secretion-associated proteinQuickGO ontologyBLASTP
121372812164632736chaperone protein clpBQuickGO ontologyBLASTP