Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:349658 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
352181352888708hypothetical proteinBLASTP
353194353673480hypothetical protein
353675354109435hypothetical proteinBLASTP
3568883604333546hypothetical proteinBLASTP
360430361113684hypothetical proteinBLASTP
3612153626511437DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
362659363132474Very short patch repair protein DNA mismatch endonuclease Vsr mismatch endonuclease VEcoKDcmQuickGO ontologyBLASTP
364727365077351hypothetical proteinBLASTP
365251365736486hypothetical proteinBLASTP
365858366232375hypothetical proteinBLASTP
369568369795228hypothetical proteinBLASTP
370668370817150hypothetical proteinBLASTP
370922371134213hypothetical proteinBLASTP
3726773771044428hypothetical proteinBLASTP
377114377533420hypothetical proteinBLASTP
3775813794911911hypothetical proteinBLASTP
3824313859763546hypothetical proteinBLASTP
3859733874061434hypothetical proteinBLASTP
387412388059648hypothetical proteinBLASTP
388056388856801hypothetical proteinBLASTP
3888533915102658hypothetical proteinBLASTP
391509392279771hypothetical proteinBLASTP
3922793936311353hypothetical proteinBLASTP
393634394200567hypothetical proteinBLASTP
3942003954861287hypothetical proteinBLASTP
395492396472981hypothetical proteinBLASTP
3965083983551848hypothetical proteinBLASTP
398357398797441hypothetical proteinBLASTP