Pre_GI: BLASTP Hits

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Query: NC_003143:2849377:2849377 Yersinia pestis CO92, complete genome

Start: 2849377, End: 2850660, Length: 1284

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is a recent Orientalis subtype isolated in the USA from a patient who died of pneumonic plague after acquiring the disease from an infected cat. Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017265:1521276:1542592154259215438751284Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative lipoprotein0820
NC_010159:1861465:1861465186146518627481284Yersinia pestis Angola, complete genomeputative lipoprotein0820
NC_004088:1801819:1821509182150918227921284Yersinia pestis KIM, complete genomehypothetical protein0820
NC_008149:2411161:2411161241116124124441284Yersinia pestis Nepal516, complete genomelipoprotein0820
NC_005810:2613456:2613456261345626147391284Yersinia pestis biovar Microtus str. 91001, complete genomeputative lipoprotein0820
NC_017154:3139614:3159311315931131605941284Yersinia pestis D106004 chromosome, complete genomeputative lipoprotein0820
NC_017160:2740870:2758920275892027602031284Yersinia pestis D182038 chromosome, complete genomeputative lipoprotein0820
NC_017168:2892000:2911776291177629130591284Yersinia pestis A1122 chromosome, complete genomeputative lipoprotein0820
NC_009708:1694685:1712954171295417142371284Yersinia pseudotuberculosis IP 31758 chromosome, complete genomelipoprotein0819
NC_010465:1724000:1744353174435317456361284Yersinia pseudotuberculosis YPIII, complete genomeprotein of unknown function DUF1870819
NC_006155:3040769:3040769304076930420731305Yersinia pseudotuberculosis IP 32953, complete genomeputative lipoprotein0810
NC_013716:1618249:1631067163106716324431377Citrobacter rodentium ICC168, complete genomeputative lipoprotein6e-152537
NC_020063:2230000:2269170226917022704861317Enterobacteriaceae bacterium strain FGI 57, complete genomehypothetical protein7e-149527
NC_021066:1393750:1413020141302014144261407Raoultella ornithinolytica B6, complete genomeglycoside hydrolase7e-148523
NC_008258:1750964:1772792177279217741111320Shigella flexneri 5 str. 8401, complete genomehypothetical protein5e-147521
NC_007613:1533024:1558078155807815593971320Shigella boydii Sb227, complete genomehypothetical protein5e-147521
NC_014310:811977:8319158319158332581344Ralstonia solanacearum PSI07 megaplasmid, complete sequencelipoprotein yddw5e-144511
NC_003296:941920:9556109556109569531344Ralstonia solanacearum GMI1000 plasmid pGMI1000MP, completehypothetical protein4e-143508
NC_012917:2362725:2367221236722123685161296Pectobacterium carotovorum subsp. carotovorum PC1, complete genomehypothetical protein2e-142506
NC_009792:1479779:1483543148354314846401098Citrobacter koseri ATCC BAA-895, complete genomehypothetical protein4e-138491
NC_013526:65495:7874678746803501605Thermobaculum terrenum ATCC BAA-798 chromosome 2, complete genomeprotein of unknown function DUF1871e-84313
NC_014210:4188448:4208888420888842105311644Nocardiopsis dassonvillei subsp. dassonvillei DSM 43111 chromosome,protein of unknown function DUF1872e-75283
NC_013510:2782240:2788014278801427896121599Thermomonospora curvata DSM 43183, complete genomeprotein of unknown function DUF1872e-69263
NC_016776:3714642:3741395374139537429031509Bacteroides fragilis 638R, complete genomehypothetical protein2e-68259
NC_006347:3760447:3787198378719837887061509Bacteroides fragilis YCH46, complete genomeputative secreted protein2e-68259
NC_003228:3690596:3695904369590436974121509Bacteroides fragilis NCTC 9343, complete genomehypothetical protein2e-68259
NC_014632:11925:1444814448156621215Ilyobacter polytropus DSM 2926 chromosome, complete genomehypothetical protein2e-67256
NC_014150:3139852:3153372315337231551891818Brachyspira murdochii DSM 12563 chromosome, complete genomeprotein of unknown function DUF1875e-48192
NC_014933:3688000:3692372369237236938291458Bacteroides helcogenes P 36-108 chromosome, complete genomehypothetical protein1e-43177
NC_010163:171148:1711481711481738682721Acholeplasma laidlawii PG-8A chromosome, complete genomehypothetical protein2e-43176
NC_010163:171148:1751911751911769301740Acholeplasma laidlawii PG-8A chromosome, complete genomehypothetical protein1e-41171
NC_003228:3690596:3703002370300237044831482Bacteroides fragilis NCTC 9343, complete genomehypothetical protein9e-42171
NC_006347:3760447:3794257379425737957771521Bacteroides fragilis YCH46, complete genomehypothetical protein7e-42171
NC_016776:3714642:3748454374845437499741521Bacteroides fragilis 638R, complete genomehypothetical protein7e-42171
NC_011565:620801:6272686272686287401473Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,hypothetical protein2e-33143
NC_011884:831905:8514808514808526671188Cyanothece sp. PCC 7425, complete genomeprotein of unknown function DUF1874e-1582.8
NC_015519:801929:8225588225588258453288Tepidanaerobacter sp. Re1 chromosome, complete genomehypothetical protein5e-1375.9
NC_006087:28490:290672906729405339Leifsonia xyli subsp. xyli str. CTCB07, complete genomehypothetical protein2e-1170.9
NS_000195:219785:2796292796292810771449Candidatus Cloacamonas acidaminovoranshypothetical protein6e-1168.9
NC_005071:1111605:1135586113558611368181233Prochlorococcus marinus str. MIT 9313, complete genomeDUF1878e-0962
NC_007513:1311957:1329152132915213303061155Synechococcus sp. CC9902, complete genomehypothetical protein8e-0858.5
NC_010546:3583568:3597997359799735992621266Cyanothece sp. ATCC 51142 chromosome circular, complete sequencehypothetical protein4e-0756.6
NC_005070:904751:9605559605559616131059Synechococcus sp. WH 8102, complete genomehypothetical protein2e-0654.3