Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_002505: Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, complete

NCBI: NC_002505

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is an epidemic serogroup of Vibrio cholerae isolated in 1971 in Bangladesh and is distinguished from the classical biotype due to hemolysin production. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
116853220059932068Island text1.9353338.309825.4414Neighbours42BLASTN+IslandViewer PAI DB168532.gbk
223856927414635578Island text2.5827939.370124.1011Neighbours21BLASTN+IslandViewer 238569.gbk
3514732*55228437553Island text1.7835336.551121.8149Neighbours21BLASTN+ PAI DB514732.gbk
486078988990629118Island text1.7983632.880625.4477Neighbours21BLASTN+IslandViewer PAI DB860789.gbk
598059599909918505Island text1.4777933.00447.6306Neighbours42BLASTNIslandViewer 980595.gbk
61507860152884320984Island text1.6212132.155928.0987Neighbours21BLASTN+IslandViewer 1507860.gbk
71550108158212332016Island text1.3085434.654729.7722Neighbours42BLASTN+IslandViewer 1550108.gbk
81892430*192509932670Island text1.6085335.285722.8221Neighbours21BLASTN+IslandViewer PAI DB1892430.gbk
91931750195259920850Island text1.5871334.029130.2248Neighbours21BLASTN+IslandViewer PAI DB1931750.gbk
102537655*256310125447Island text2.1280733.551224.8873Neighbours42BLASTN2537655.gbk