Pre_GI Gene

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Host: NC_002505 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002505:238569 Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, complete

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is an epidemic serogroup of Vibrio cholerae isolated in 1971 in Bangladesh and is distinguished from the classical biotype due to hemolysin production. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
23728923860813203-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
238569239357789hypothetical proteinBLASTP
2393542404031050lipopolysaccharide biosynthesis protein putativeQuickGO ontologyBLASTP
2404002414401041ADP-heptose--LPS heptosyltransferase IIQuickGO ontologyBLASTP
2414372426361200hypothetical proteinBLASTP
242638243204567transferase hexapeptide repeat familyQuickGO ontologyBLASTP
2432122449841773hypothetical proteinBLASTP
245143246087945ADP-L-glycero-D-mannoheptose-6-epimeraseQuickGO ontologyBLASTP
2465292479261398mannose-1-phosphate guanylyltransferaseQuickGO ontologyBLASTP
2479292493201392phosphomannomutaseQuickGO ontologyBLASTP
2493232504441122GDP-mannose 46-dehydrataseQuickGO ontologyBLASTP
2504552515581104perosamine synthaseQuickGO ontologyBLASTP
2515552529461392rfbG proteinQuickGO ontologyBLASTP
252918253712795lipopolysaccharideO-antigen transport proteinQuickGO ontologyBLASTP
253651254466816lipopolysaccharideO-antigen transport proteinQuickGO ontologyBLASTP
254505254747243acyl carrier protein putativeQuickGO ontologyBLASTP
2547532561681416rfbL proteinQuickGO ontologyBLASTP
2561772573011125iron-containing alcohol dehydrogenase family protein RfbMQuickGO ontologyBLASTP
2572922597692478acyl protein synthaseacyl-CoA reductase RfbNQuickGO ontologyBLASTP
259839260405567acetyltransferase RfbO CysELacALpxANodL familyQuickGO ontologyBLASTP
26055526063581IS1004 transposaseQuickGO ontologyBLASTP
262098262319222rfbT-related proteinQuickGO ontologyBLASTP
262326262670345transposase OrfAB subunit AQuickGO ontologyBLASTP
262667263539873transposase OrfAB subunit BQuickGO ontologyBLASTP
263536264219684rfbT proteinQuickGO ontologyBLASTP
2642542654861233lipopolysaccharide biosynthesis protein RfbVQuickGO ontologyBLASTP
2653742672391866mannosyl-transferaseQuickGO ontologyBLASTP
267300267440141hypothetical proteinBLASTP
267392268363972UDP-glucose 4-epimeraseQuickGO ontologyBLASTP
268371268925555galactosyl-transferase putativeQuickGO ontologyBLASTP
2690682704351368hypothetical proteinBLASTP
2706972719351239hypothetical proteinBLASTP
271990272562573hypothetical proteinBLASTP
272562273485924D-isomer specific 2-hydroxyacid dehydrogenase family proteinQuickGO ontologyBLASTP
273478274146669hypothetical proteinBLASTP