Pre_GI Gene

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Host: NC_002505 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002505:1550108 Vibrio cholerae O1 biovar eltor str. N16961 chromosome I, complete

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: This is an epidemic serogroup of Vibrio cholerae isolated in 1971 in Bangladesh and is distinguished from the classical biotype due to hemolysin production. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
15496621550123462RTX toxin activating proteinQuickGO ontologyBLASTP
1550108156378413677RTX toxin RtxAQuickGO ontologyBLASTP
15641521564376225RstC proteinQuickGO ontologyBLASTP
15644701564844375RstB1 proteinQuickGO ontologyBLASTP
156482215659011080RstA1 proteinQuickGO ontologyBLASTP
15660271566365339transcriptional repressor RstRQuickGO ontologyBLASTP
15669671567341375cholera enterotoxin B subunitQuickGO ontologyBLASTP
15673381568114777cholera enterotoxin A subunitQuickGO ontologyBLASTP
156821315694121200zona occludens toxinQuickGO ontologyBLASTP
15694091569702294accessory cholera enterotoxinQuickGO ontologyBLASTP
156969915709821284hypothetical proteinBLASTP
15709931571241249colonization factorQuickGO ontologyBLASTP
15713771571760384RstB2 proteinQuickGO ontologyBLASTP
157173815728171080RstA2 proteinQuickGO ontologyBLASTP
15729431573281339transcriptional repressor RstRQuickGO ontologyBLASTP
15737711574355585hypothetical proteinBLASTP
15743481574515168hypothetical proteinBLASTP
15745931575285693hypothetical proteinBLASTP
15754151575699285hypothetical proteinBLASTP
157570415772721569phage replication protein CriQuickGO ontologyBLASTP
15790391579206168hypothetical proteinBLASTP
15791991579366168hypothetical proteinBLASTP
15794441580136693hypothetical proteinBLASTP
15802661580550285hypothetical proteinBLASTP
158055515821231569phage replication protein CriQuickGO ontologyBLASTP