Pre_GI: BLASTP Hits

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Query: NC_017297:33519:63062 Clostridium botulinum F str. 230613 chromosome, complete genome

Start: 63062, End: 63137, Length: 76

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017297:33519:70069700697014476Clostridium botulinum F str. 230613 chromosome, complete genometRNA-Phe2e-0651.2
NC_014393:139690:16147916147916155476Clostridium cellulovorans 743B chromosome, complete genometRNA-Phe2e-0651.2
NC_009495:3340000:33451333345133334520876Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Phe2e-0651.2
NC_009495:38000:68033680336810876Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Phe2e-0651.2
NC_009495:38000:75038750387511376Clostridium botulinum A str. ATCC 3502 chromosome, complete genometRNA-Phe2e-0651.2
NC_009697:3316000:33211223321122332119776Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Phe2e-0651.2
NC_009697:38000:67841678416791676Clostridium botulinum A str. ATCC 19397 chromosome, completetRNA-Phe2e-0651.2
NC_009698:3211131:32182293218229321830476Clostridium botulinum A str. Hall chromosome, complete genometRNA-Phe2e-0651.2
NC_009698:38000:67842678426791776Clostridium botulinum A str. Hall chromosome, complete genometRNA-Phe2e-0651.2
NC_009699:33452:62928629286300376Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Phe2e-0651.2
NC_009699:33452:69867698676994276Clostridium botulinum F str. Langeland chromosome, complete genometRNA-Phe2e-0651.2
NC_014393:92500:12808512808512816076Clostridium cellulovorans 743B chromosome, complete genometRNA-Phe2e-0651.2