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Query: NC_017160:3094768:3110093 Yersinia pestis D182038 chromosome, complete genome

Start: 3110093, End: 3110839, Length: 747

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_003143:3191246:319529131952913196061771Yersinia pestis CO92, complete genomehypothetical protein2e-138491
NC_017154:2876545:288055928805592881305747Yersinia pestis D106004 chromosome, complete genomehypothetical protein3e-138490
NC_014029:3171627:318512631851263185872747Yersinia pestis Z176003 chromosome, complete genomehypothetical protein3e-138490
NC_004088:1510467:152396615239661524712747Yersinia pestis KIM, complete genomehypothetical protein3e-138490
NC_008149:1440371:145388614538861454632747Yersinia pestis Nepal516, complete genomehypothetical protein3e-138490
NC_008150:2574794:257888325788832579629747Yersinia pestis Antiqua, complete genomehypothetical protein3e-138490
NC_005810:3021913:302586030258603026747888Yersinia pestis biovar Microtus str. 91001, complete genomehypothetical protein2e-135481
NC_009381:2491427:249537424953742496261888Yersinia pestis Pestoides F chromosome, complete genomehypothetical protein2e-135481
NC_009708:1403434:141547114154711416391921Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein7e-134476
NC_010465:1427170:145132314513231452243921Yersinia pseudotuberculosis YPIII, complete genomehypothetical protein7e-134476
NC_010634:3250810:325622732562273257147921Yersinia pseudotuberculosis PB1/+, complete genomehypothetical protein7e-134476
NC_006155:3333303:333874333387433339663921Yersinia pseudotuberculosis IP 32953, complete genomehypothetical protein7e-134476