Query: NC_012658:3678000 Clostridium botulinum Ba4 str. 657 chromosome, complete genome
Start: 3678000, End: 3702099, Length: 24100
Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_010520:3674883* | 3674883 | 3698984 | 24102 | Clostridium botulinum A3 str. Loch Maree, complete genome | 0 | 5055 | BLASTN svg | BLASTP svg |
NC_004557:2037500 | 2037500 | 2057599 | 20100 | Clostridium tetani E88, complete genome | 0 | 3901 | BLASTN svg | BLASTP svg |
NC_014328:2990790* | 2990790 | 3032099 | 41310 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 0 | 2924 | BLASTN svg | BLASTP svg |
NC_010001:1702350* | 1702350 | 1729198 | 26849 | Clostridium phytofermentans ISDg, complete genome | 4e-178 | 632 | BLASTN svg | BLASTP svg |
NC_009089:4177117 | 4177117 | 4200707 | 23591 | Clostridium difficile 630, complete genome | 6e-103 | 383 | BLASTN svg | BLASTP svg |
NC_014328:303063* | 303063 | 377862 | 74800 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 6e-100 | 373 | BLASTN svg | BLASTP svg |
NC_021182:3525523* | 3525523 | 3566737 | 41215 | Clostridium pasteurianum BC1, complete genome | 2e-56 | 228 | BLASTN svg | BLASTP svg |
NC_010001:1745089 | 1745089 | 1775894 | 30806 | Clostridium phytofermentans ISDg, complete genome | 2e-29 | 139 | BLASTN svg | BLASTP svg |
NC_016012:104500* | 104500 | 125194 | 20695 | Candidatus Arthromitus sp. SFB-rat-Yit, complete genome | 6e-29 | 137 | BLASTN svg | BLASTP svg |
NC_009089:3935500* | 3935500 | 3979165 | 43666 | Clostridium difficile 630, complete genome | 2e-28 | 135 | BLASTN svg | BLASTP svg |
NC_003366:461602* | 461602 | 484355 | 22754 | Clostridium perfringens str. 13, complete genome | 9e-22 | 113 | BLASTN svg | BLASTP svg |
NC_019970:743497* | 743497 | 761798 | 18302 | Thermoanaerobacterium thermosaccharolyticum M0795, complete genome | 9e-22 | 113 | BLASTN svg | BLASTP svg |
NC_008261:421000* | 421000 | 437700 | 16701 | Clostridium perfringens ATCC 13124, complete genome | 5e-20 | 107 | BLASTN svg | BLASTP svg |
NC_008262:419726* | 419726 | 440602 | 20877 | Clostridium perfringens SM101, complete genome | 8e-16 | 93.7 | BLASTN svg | BLASTP svg |
NC_021175:1597613 | 1597613 | 1621108 | 23496 | Streptococcus oligofermentans AS 1.3089, complete genome | 5e-11 | 77.8 | BLASTN svg | BLASTP svg |
NC_013895:1332832 | 1332832 | 1380099 | 47268 | Clostridiales genomosp. BVAB3 str. UPII9-5 chromosome, complete | 5e-11 | 77.8 | BLASTN svg | BLASTP svg |
NC_011898:1762000* | 1762000 | 1785028 | 23029 | Clostridium cellulolyticum H10, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_010001:404066 | 404066 | 423599 | 19534 | Clostridium phytofermentans ISDg, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_020291:5808856 | 5808856 | 5852592 | 43737 | Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_009089:581655 | 581655 | 606563 | 24909 | Clostridium difficile 630, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_003454:249304* | 249304 | 269788 | 20485 | Fusobacterium nucleatum subsp. nucleatum ATCC 25586, complete | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |