Pre_GI: BLASTP Hits

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Query: NC_007384:1737885:1744397 Shigella sonnei Ss046, complete genome

Start: 1744397, End: 1745278, Length: 882

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic in China in the 1950s. A leading cause of dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. This extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016822:1818897:182371918237191824600882Shigella sonnei 53G, complete genomearomatic amino acid exporter9e-152536
NC_013941:1857724:187217418721741873055882Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein3e-150531
NC_013008:1971662:198128619812861982167882Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein3e-150531
NC_011353:1971145:198231019823101983191882Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein3e-150531
NC_002655:2015000:201988220198822020763882Escherichia coli O157:H7 EDL933, complete genomehypothetical protein3e-150531
NC_017328:1835108:184345518434551844336882Shigella flexneri 2002017 chromosome, complete genomehypothetical protein5e-150530
NC_004741:1823000:182785818278581828739882Shigella flexneri 2a str. 2457T, complete genomehypothetical protein5e-150530
NC_004337:1783645:179013517901351791016882Shigella flexneri 2a str. 301, complete genomehypothetical protein5e-150530
NC_010498:1700447:170462317046231705504882Escherichia coli SMS-3-5, complete genomehypothetical protein1e-149528
NC_008258:1784637:178951617895161790340825Shigella flexneri 5 str. 8401, complete genomehypothetical protein2e-140498
NC_002695:2056545:206771020677102068534825Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein1e-139496
NC_011750:1809943:182346818234681824292825Escherichia coli IAI39 chromosome, complete genomehypothetical protein1e-138492
NC_012917:2362725:236272523627252363636912Pectobacterium carotovorum subsp. carotovorum PC1, complete genomehypothetical protein6e-95347
NC_008752:1523768:152376815237681524679912Acidovorax avenae subsp. citrulli AAC00-1, complete genomeprotein of unknown function DUF6, transmembrane8e-82303
NC_014323:3669704:367214836721483673071924Herbaspirillum seropedicae SmR1 chromosome, complete genomedrug/metabolite transporter (DMT) superfamily permease7e-81300
NC_007947:577315:579723579723580640918Methylobacillus flagellatus KT, complete genomeprotein of unknown function DUF6, transmembrane1e-56220
NC_015563:6357653:635671063567106357696987Delftia sp. Cs1-4 chromosome, complete genomehypothetical protein5e-51201
NC_014656:1536540:155667915566791557635957Bifidobacterium longum subsp. longum BBMN68 chromosome, completemethyl viologen exporter2e-42172
NC_010511:5467009:548430854843085485210903Methylobacterium sp. 4-46 chromosome, complete genomehypothetical protein6e-0858.5