Pre_GI: OUP Neighbours

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Query: NC_008767:136958 Neisseria meningitidis FAM18, complete genome

D: 42.4421

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Number of Neighbours: 31




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_013416:1588369Aggregatibacter actinomycetemcomitans D11S-1, complete genome76.636 %Subject Query26.0305
NC_003116:1488576*Neisseria meningitidis Z2491, complete genome75.4718 %Subject Query29.0157
NC_003116:2063500*Neisseria meningitidis Z2491, complete genome75.1532 %Subject Query29.3522
NC_002946:618439*Neisseria gonorrhoeae FA 1090, complete genome75.2328 %Subject Query29.5598
NC_015572:293665*Methylomonas methanica MC09 chromosome, complete genome75.4779 %Subject Query29.572
NC_010120:1814592*Neisseria meningitidis 053442, complete genome75.3707 %Subject Query30.1556
NC_008767:2160000*Neisseria meningitidis FAM18, complete genome81.0539 %Subject Query30.2286
NC_015572:2541968Methylomonas methanica MC09 chromosome, complete genome75.1685 %Subject Query30.5265
NC_003112:744476*Neisseria meningitidis MC58, complete genome78.5692 %Subject Query30.6481
NC_008767:927810Neisseria meningitidis FAM18, complete genome79.5803 %Subject Query31.1649
NC_015572:1974000*Methylomonas methanica MC09 chromosome, complete genome75.0245 %Subject Query31.2378
NC_008767:804655*Neisseria meningitidis FAM18, complete genome76.2102 %Subject Query31.3551
NC_003112:364869Neisseria meningitidis MC58, complete genome76.1336 %Subject Query31.3594
NC_002946:1902642*Neisseria gonorrhoeae FA 1090, complete genome79.0625 %Subject Query32.1741
NC_003116:1518110*Neisseria meningitidis Z2491, complete genome75.337 %Subject Query32.2145
NC_003112:603879*Neisseria meningitidis MC58, complete genome75.8793 %Subject ←→ Query32.7335
NC_003112:1685330Neisseria meningitidis MC58, complete genome76.106 %Subject ←→ Query32.9463
NC_003112:844000Neisseria meningitidis MC58, complete genome75.9283 %Subject ←→ Query33.2077
NC_010120:2055803*Neisseria meningitidis 053442, complete genome77.2365 %Subject ←→ Query34.0893
NC_015581:128350*Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome76.682 %Subject ←→ Query34.2108
NC_003116:1018813*Neisseria meningitidis Z2491, complete genome75.3493 %Subject ←→ Query35.3771
NC_008767:2126854*Neisseria meningitidis FAM18, complete genome76.201 %Subject ←→ Query37.8283
NC_010120:2098000*Neisseria meningitidis 053442, complete genome75.867 %Subject ←→ Query38.0974
NC_014752:98117*Neisseria lactamica ST-640, complete genome87.5735 %Subject ←→ Query38.3488
NC_008767:84950*Neisseria meningitidis FAM18, complete genome78.9614 %Subject ←→ Query39.6431
NC_003112:96815*Neisseria meningitidis MC58, complete genome79.3658 %Subject ←→ Query39.9852
NC_015572:4209000*Methylomonas methanica MC09 chromosome, complete genome78.6458 %Subject ←→ Query40.0218
NC_010120:2029880*Neisseria meningitidis 053442, complete genome91.3082 %Subject ←→ Query40.7305
NC_003116:93576*Neisseria meningitidis Z2491, complete genome91.4798 %Subject ←→ Query41.4266
NC_002946:1786000*Neisseria gonorrhoeae FA 1090, complete genome86.5135 %Subject ←→ Query41.5742
NC_003112:149593*Neisseria meningitidis MC58, complete genome95.5116 %Subject ←→ Query43.0866