Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:2160000 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
216045021615531104peptide chain release factor 2QuickGO ontologyBLASTP
21616562162558903possible lipoproteinQuickGO ontologyBLASTP
21628912163340450putative integral membrane proteinQuickGO ontologyBLASTP
21634142163722309putative periplasmic proteinQuickGO ontology
21638142164680867hypothetical proteinBLASTP
21646492165416768hypothetical proteinBLASTP
21654382166025588putative ECF-family RNA polymerase sigma factorQuickGO ontologyBLASTP
21664422166882441putative lipoproteinQuickGO ontologyBLASTP
21673562168321966insertion element IS1655 transposaseQuickGO ontologyBLASTP
21688652169518654insertion element IS1016 transposaseQuickGO ontologyBLASTP
21695902170192603hypothetical proteinBLASTP
217022621714971272phosphoribosylamine--glycine ligaseQuickGO ontologyBLASTP
21716552171972318hypothetical proteinBLASTP
21720242172635612hypothetical proteinBLASTP
21726982173633936electron transfer flavoprotein alpha-subunitQuickGO ontologyBLASTP
21736442174393750electron transfer flavoprotein beta-subunitQuickGO ontologyBLASTP
21746192175587969lipopolysaccharide heptosyltransferase IQuickGO ontologyBLASTP
21756252176260636putative nicotinamidaseQuickGO ontologyBLASTP
21763752177055681hypothetical proteinBLASTP
217731321783501038glyceraldehyde 3-phosphate dehydrogenase CQuickGO ontologyBLASTP
217876121813552595DNA mismatch repair proteinQuickGO ontologyBLASTP
21814782181969492putative acetyltransferaseQuickGO ontologyBLASTP
21819732182371399putative periplasmic proteinQuickGO ontologyBLASTP