Pre_GI Gene

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Host: NC_010120 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010120:1814592 Neisseria meningitidis 053442, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
181459218160131422oxygen-independent coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
181636618179401575inorganic phosphate transporter PiT familyQuickGO ontologyBLASTP
18179161818167252conserved hypothetical proteinBLASTP
181826518193651101conserved hypothetical proteinBLASTP
18194841820425942adhesin MafA2QuickGO ontologyBLASTP
182042918219251497adhesin MafB2QuickGO ontologyBLASTP
18219401822170231conserved hypothetical proteinBLASTP
18225591823056498conserved hypothetical proteinBLASTP
18230531823472420conserved hypothetical proteinBLASTP
18237201823992273conserved hypothetical proteinBLASTP
18241131824658546conserved hypothetical proteinBLASTP
18247941825468675conserved hypothetical proteinBLASTP
18254461825727282conserved hypothetical proteinBLASTP
18259371826392456conserved hypothetical proteinBLASTP
18264611826838378conserved hypothetical proteinBLASTP
182690218280351134conserved hypothetical proteinBLASTP
18281221828397276iron-regulated protein FrpCQuickGO ontologyBLASTP
18284141829124711FrpC operon proteinQuickGO ontologyBLASTP
18295731829848276putative endonucleaseQuickGO ontologyBLASTP
182984518311281284MFS transporter PAT family beta-lactamase induction signal transducer AmpGQuickGO ontologyBLASTP
183127618326941419glutamine synthetaseQuickGO ontologyBLASTP
18335151834324810shikimate dehydrogenaseQuickGO ontologyBLASTP
18343261835027702monofunctional biosynthetic peptidoglycan transglycosylaseQuickGO ontologyBLASTP
1835230183530576tRNA-PheQuickGO ontologyBLASTP
18354961836230735ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
18363041836774471conserved hypothetical proteinBLASTP